Editorial: 2021: a new year for the WHO

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Latest Research

  • Letter
    | Open Access

    Analysis of global smoking prevalence trends from 2009 to 2017 demonstrates that, when implemented, national-level tobacco control policies are highly effective; however, considerable gaps remain in the universal adoption of anti-tobacco interventions.

    • Luisa S. Flor
    • , Marissa B. Reitsma
    • , Vinay Gupta
    • , Marie Ng
    •  & Emmanuela Gakidou
  • Article |

    Personalized neoantigen vaccination in patients with melanoma elicits durable and specific memory T cell clones that have cytotoxic gene signatures and can diversify to include nonvaccine neoantigen specificities.

    • Zhuting Hu
    • , Donna E. Leet
    • , Rosa L. Allesøe
    • , Giacomo Oliveira
    • , Shuqiang Li
    • , Adrienne M. Luoma
    • , Jinyan Liu
    • , Juliet Forman
    • , Teddy Huang
    • , J. Bryan Iorgulescu
    • , Rebecca Holden
    • , Siranush Sarkizova
    • , Satyen H. Gohil
    • , Robert A. Redd
    • , Jing Sun
    • , Liudmila Elagina
    • , Anita Giobbie-Hurder
    • , Wandi Zhang
    • , Lauren Peter
    • , Zoe Ciantra
    • , Scott Rodig
    • , Oriol Olive
    • , Keerthi Shetty
    • , Jason Pyrdol
    • , Mohamed Uduman
    • , Patrick C. Lee
    • , Pavan Bachireddy
    • , Elizabeth I. Buchbinder
    • , Charles H. Yoon
    • , Donna Neuberg
    • , Bradley L. Pentelute
    • , Nir Hacohen
    • , Kenneth J. Livak
    • , Sachet A. Shukla
    • , Lars Rønn Olsen
    • , Dan H. Barouch
    • , Kai W. Wucherpfennig
    • , Edward F. Fritsch
    • , Derin B. Keskin
    • , Catherine J. Wu
    •  & Patrick A. Ott
  • Article |

    In an inpatient, randomized controlled crossover trial, participants consumed 550–700 kcal day−1 fewer calories when following a plant-based, low-fat diet with a high glycemic load compared with an animal-based, low-carbohydrate diet with a low glycemic load; weight loss was comparable between the two diets and there were no significant differences in hunger or enjoyment of the meals.

    • Kevin D. Hall
    • , Juen Guo
    • , Amber B. Courville
    • , James Boring
    • , Robert Brychta
    • , Kong Y. Chen
    • , Valerie Darcey
    • , Ciaran G. Forde
    • , Ahmed M. Gharib
    • , Isabelle Gallagher
    • , Rebecca Howard
    • , Paule V. Joseph
    • , Lauren Milley
    • , Ronald Ouwerkerk
    • , Klaudia Raisinger
    • , Irene Rozga
    • , Alex Schick
    • , Michael Stagliano
    • , Stephan Torres
    • , Mary Walter
    • , Peter Walter
    • , Shanna Yang
    •  & Stephanie T. Chung
  • Perspective |

    A comprehensive strategy for the next steps to ensure vaccination of the global population against SARS-CoV-2 is now required, and key steps and challenges are detailed in this Perspective.

    • Jerome H. Kim
    • , Florian Marks
    •  & John D. Clemens
  • Article |

    Functional interplay of sex hormones in estrogen receptor–positive breast cancer unveils the therapeutic potential of androgen receptor agonists.

    • Theresa E. Hickey
    • , Luke A. Selth
    • , Kee Ming Chia
    • , Geraldine Laven-Law
    • , Heloisa H. Milioli
    • , Daniel Roden
    • , Shalini Jindal
    • , Mun Hui
    • , Jessica Finlay-Schultz
    • , Esmaeil Ebrahimie
    • , Stephen N. Birrell
    • , Suzan Stelloo
    • , Richard Iggo
    • , Sarah Alexandrou
    • , C. Elizabeth Caldon
    • , Tarek M. Abdel-Fatah
    • , Ian O. Ellis
    • , Wilbert Zwart
    • , Carlo Palmieri
    • , Carol A. Sartorius
    • , Alex Swarbrick
    • , Elgene Lim
    • , Jason S. Carroll
    •  & Wayne D. Tilley

News & Comment

Milestone

Cancer Milestones

Chris Ryan

Cancer Milestones

The ancient physician Hippocrates described the projection of blood vessels from a collection of cells as ‘karkinos’, the Greek word for crab.

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