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  • Letter |

    A longitudinal survey of maternal antiviral antibodies in newborns provides a blueprint for understanding infectious disease susceptibility and vaccine development, and inform vaccine scheduling in newborn children.

    • Christian Pou
    • , Dieudonné Nkulikiyimfura
    • , Ewa Henckel
    • , Axel Olin
    • , Tadepally Lakshmikanth
    • , Jaromir Mikes
    • , Jun Wang
    • , Yang Chen
    • , Anna Karin Bernhardsson
    • , Anna Gustafsson
    • , Kajsa Bohlin
    •  & Petter Brodin
  • Letter |

    In a nested case-control study from the China Kadoorie Biobank, lowering blood low-density lipoprotein cholesterol levels confers lower risk for ischemic stroke but elevated risk for intracerebral hemorrhage, which was confirmed by genetic Mendelian randomization analyses.

    • Luanluan Sun
    • , Robert Clarke
    • , Derrick Bennett
    • , Yu Guo
    • , Robin G. Walters
    • , Michael Hill
    • , Sarah Parish
    • , Iona Y. Millwood
    • , Zheng Bian
    • , Yiping Chen
    • , Canqing Yu
    • , Jun Lv
    • , Rory Collins
    • , Junshi Chen
    • , Richard Peto
    • , Liming Li
    • , Zhengming Chen
    • , Junshi Chen
    • , Zhengming Chen
    • , Robert Clarke
    • , Rory Collins
    • , Yu Guo
    • , Liming Li
    • , Jun Lv
    • , Richard Peto
    • , Robin Walters
    • , Daniel Avery
    • , Derrick Bennett
    • , Ruth Boxall
    • , Fiona Bragg
    • , Yumei Chang
    • , Yiping Chen
    • , Zhengming Chen
    • , Robert Clarke
    • , Huaidong Du
    • , Simon Gilbert
    • , Alex Hacker
    • , Michael Holmes
    • , Christiana Kartsonaki
    • , Rene Kerosi
    • , Garry Lancaster
    • , Kuang Lin
    • , John McDonnell
    • , Iona Millwood
    • , Qunhua Nie
    • , Jayakrishnan Radhakrishnan
    • , Paul Ryder
    • , Sam Sansome
    • , Dan Schmidt
    • , Rajani Sohoni
    • , Iain Turnbull
    • , Robin Walters
    • , Jenny Wang
    • , Lin Wang
    • , Neil Wright
    • , Ling Yang
    • , Xiaoming Yang
    • , Zheng Bian
    • , Yu Guo
    • , Xiao Han
    • , Can Hou
    • , Biao Jing
    • , Chao Liu
    • , Jun Lv
    • , Pei Pei
    • , Yunlong Tan
    • , Canqing Yu
    • , Zengchang Pang
    • , Ruqin Gao
    • , Shanpeng Li
    • , Shaojie Wang
    • , Yongmei Liu
    • , Ranran Du
    • , Yajing Zang
    • , Liang Cheng
    • , Xiaocao Tian
    • , Hua Zhang
    • , Yaoming Zhai
    • , Feng Ning
    • , Xiaohui Sun
    • , Feifei Li
    • , Silu Lv
    • , Junzheng Wang
    • , Wei Hou
    • , Mingyuan Zeng
    • , Ge Jiang
    • , Xue Zhou
    • , Liqiu Yang
    • , Hui He
    • , Bo Yu
    • , Yanjie Li
    • , Qinai Xu
    • , Quan Kang
    • , Ziyan Guo
    • , Dan Wang
    • , Ximin Hu
    • , Hongmei Wang
    • , Jinyan Chen
    • , Yan Fu
    • , Zhenwang Fu
    • , Xiaohuan Wang
    • , Min Weng
    • , Zhendong Guo
    • , Shukuan Wu
    • , Yilei Li
    • , Huimei Li
    • , Zhifang Fu
    • , Ming Wu
    • , Yonglin Zhou
    • , Jinyi Zhou
    • , Ran Tao
    • , Jie Yang
    • , Jian Su
    • , Fang Liu
    • , Jun Zhang
    • , Yihe Hu
    • , Yan Lu
    • , Liangcai Ma
    • , Aiyu Tang
    • , Shuo Zhang
    • , Jianrong Jin
    • , Jingchao Liu
    • , Zhenzhu Tang
    • , Naying Chen
    • , Ying Huang
    • , Mingqiang Li
    • , Jinhuai Meng
    • , Rong Pan
    • , Qilian Jiang
    • , Jian Lan
    • , Yun Liu
    • , Liuping Wei
    • , Liyuan Zhou
    • , Ningyu Chen
    • , Ping Wang
    • , Fanwen Meng
    • , Yulu Qin
    • , Sisi Wang
    • , Xianping Wu
    • , Ningmei Zhang
    • , Xiaofang Chen
    • , Weiwei Zhou
    • , Guojin Luo
    • , Jianguo Li
    • , Xiaofang Chen
    • , Xunfu Zhong
    • , Jiaqiu Liu
    • , Qiang Sun
    • , Pengfei Ge
    • , Xiaolan Ren
    • , Caixia Dong
    • , Hui Zhang
    • , Enke Mao
    • , Xiaoping Wang
    • , Tao Wang
    • , Xi Zhang
    • , Ding Zhang
    • , Gang Zhou
    • , Shixian Feng
    • , Liang Chang
    • , Lei Fan
    • , Yulian Gao
    • , Tianyou He
    • , Huarong Sun
    • , Pan He
    • , Chen Hu
    • , Xukui Zhang
    • , Huifang Wu
    • , Min Yu
    • , Ruying Hu
    • , Hao Wang
    • , Yijian Qian
    • , Chunmei Wang
    • , Kaixu Xie
    • , Lingli Chen
    • , Yidan Zhang
    • , Dongxia Pan
    • , Qijun Gu
    • , Yuelong Huang
    • , Biyun Chen
    • , Li Yin
    • , Huilin Liu
    • , Zhongxi Fu
    • , Qiaohua Xu
    • , Xin Xu
    • , Hao Zhang
    • , Huajun Long
    • , Xianzhi Li
    • , Libo Zhang
    •  & Zhe Qiu
  • Letter |

    iPSC-derived brain organoids from patients with neurodevelopmental disease reveal dysfunction in neural progenitors underlying impaired migration of developing neurons in periventricular heterotopia.

    • Johannes Klaus
    • , Sabina Kanton
    • , Christina Kyrousi
    • , Ane Cristina Ayo-Martin
    • , Rossella Di Giaimo
    • , Stephan Riesenberg
    • , Adam C. O’Neill
    • , J. Gray Camp
    • , Chiara Tocco
    • , Malgorzata Santel
    • , Ejona Rusha
    • , Micha Drukker
    • , Mariana Schroeder
    • , Magdalena Götz
    • , Stephen P. Robertson
    • , Barbara Treutlein
    •  & Silvia Cappello
  • Article |

    Defects in the regulation of leptin gene expression can lead to a hypoleptinemic, leptin-responsive form of obesity.

    • Olof S. Dallner
    • , Jill M. Marinis
    • , Yi-Hsueh. Lu
    • , Kivanc Birsoy
    • , Emory Werner
    • , Gulya Fayzikhodjaeva
    • , Brian D. Dill
    • , Henrik Molina
    • , Arden Moscati
    • , Zoltán Kutalik
    • , Pedro Marques-Vidal
    • , Tuomas O. Kilpeläinen
    • , Niels Grarup
    • , Allan Linneberg
    • , Yinxin Zhang
    • , Roger Vaughan
    • , Ruth J. F. Loos
    • , Mitchell A. Lazar
    •  & Jeffrey M. Friedman

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