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Volume 8 Issue 12, December 2007

The Council of Science Editors recently organized the participation of 232 journals worldwide in its 2007 Global Theme Issue on Poverty and Human Development. In this issue, Nature Immunology is pleased to contribute two commentaries by Farrar (p 1277) and Gotch and Gilmour (p 1273) discussing this topic. Articles contributed by Nature Publishing Group are freely accessible at http://www.nature.com/povhumdev/index.html. Artwork by Lewis Long.

Volume 8 Issue 12

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Editorial

  • Diverse measures are needed to combat the detrimental effects of poverty on children in developing and developed nations.

    Editorial

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Essay

  • Jack Strominger recounts his seminal work and contributions to understanding bacterial cell wall components, and thus how penicillin functions, and the implications of these discoveries for immunology.

    • Jack L Strominger
    Essay
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Commentary

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News & Views

  • Four new papers focused on how interleukin 10–producing cells are induced have led to some unexpected and intriguing observations on the nature of interleukin 17–producing T helper cells.

    • Dragana Jankovic
    • Giorgio Trinchieri
    News & Views

  • Many additional effects in HIV pathogenesis are now described for the chemokine receptor CCR5, long recognized as an important coreceptor for HIV, and its ligand CCL3L1.

    • Michael M Lederman
    • Scott F Sieg
    News & Views

  • Thymus-derived regulatory T cells are thought to suppress target cells by either a cell contact–dependent mechanism or the production of inhibitory cytokines. A new study suggests a third strategy of apoptosis induced by the consumption of interleukin 2 and other T cell growth factors by regulatory T cells.

    • Alexander Scheffold
    • Kenneth M Murphy
    • Thomas Höfer
    News & Views

  • Inhibition of phagocyte activity depends on the ligation of SIRP-α by CD47. New findings show that Sirpa polymorphisms influence the engraftment and tolerance of xenogeneic transplants in NOD-SCID mice.

    • Hitoshi Takizawa
    • Markus G Manz
    News & Views

  • Interleukin 15 (IL-15) is essential for natural killer (NK) cell development and function, and the adaptor DAP10 transmits important signals in NK cells. New work shows that IL-15 and DAP10 cross regulate each other.

    • Francesco Colucci
    News & Views
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Research Highlights

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Review Article

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Article

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Erratum

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Corrigendum

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