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Volume 21 Issue 4, April 2020

Volume 21 Issue 4

MAIT cell antigen recognition

Mucosa-associated invariant T (MAIT) cells recognize vitamin B metabolites presented by the molecule MR1. Rossjohn and colleagues generate multiple altered metabolite ligands and determine their structures in the context of MR1 and the TCR to develop a generalized framework for MAIT cell antigen recognition.

See Awad et al.

Image: Erica Tandori. Cover Design: Erin Dewalt.

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