Volume 2 Issue 4, April 2001

The epithelial and M cells of the intestine are credited with protecting the host from pathogen invasion through the gastrointestinal tract. Rescigno et al. report on page 361 that dendritic cells can form tight junctions and intercalate between epithelial cells, a location from which they are well positioned to contribute to host defense. See also the News & Views by Gewirtz and Madara on page 288. Welded steel relief of dendritic cells by Christopher Cassidy; original micrograph from Rescigno et al.

Editorial

Peer-to-peer

Editorial 01 Apr 2001

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Correspondence

Trouble with peer review

Benedita Rocha
Correspondence 01 Apr 2001
CTLA-4 up-regulation plays a role in tolerance mediated by CD45

Nicholas R. StC. Sinclair
Correspondence 01 Apr 2001

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Commentary

Autoimmunity versus horror autotoxicus: The struggle for recognition

Historical insight: Paul Ehrlich's dictum of horror autotoxicus and the changing orientation of the field inhibited acceptance of the reality of autoimmune disease.

Arthur M. Silverstein
Commentary 01 Apr 2001

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News & Views

Policing the regulators

Shimon Sakaguchi
News & Views 01 Apr 2001
Chemokines: Not just leukocyte chemoattractants in the promotion of cancer

Robert M. Strieter
News & Views 01 Apr 2001
Extolling the diversity of bacterial endotoxins

Douglas T. Golenbock
Matthew J. Fenton
News & Views 01 Apr 2001
Periscope, up! Monitoring microbes in the intestine

Andrew T. Gewirtz
James L. Madara
News & Views 01 Apr 2001

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Round-up

Immunology highlights from the recent literature

Round-up 01 Apr 2001

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Review Article

A fresh look at tumor immunosurveillance and immunotherapy

Mark J. Smyth
Dale I. Godfrey
Joseph A. Trapani
Review Article 01 Apr 2001

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Article

Thymic selection of CD4⁺CD25⁺ regulatory T cells induced by an agonist self-peptide

Martha S. Jordan
Alina Boesteanu
Andrew J. Caton
Article 01 Apr 2001
Defining the specific physiological requirements for c-Myc in T cell development

Nataki C. Douglas
Harris Jacobs
Adrian C. Hayday
Article 01 Apr 2001
Gene regulation mediated by calcium signals in T lymphocytes

Stefan Feske
Jena Giltnane
Anjana Rao
Article 01 Apr 2001
A point mutation in CD28 distinguishes proliferative signals from survival signals

Klaus Okkenhaug
Linda Wu
Robert Rottapel
Article 01 Apr 2001
Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity

Kazunori Aoki
Masayuki Kurooka
Gary J. Nabel
Article 01 Apr 2001
A CD14-independent LPS receptor cluster

Kathy Triantafilou
Martha Triantafilou
Russell L. Dedrick
Article 01 Apr 2001
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

Catherine Werts
Richard I. Tapping
Richard J. Ulevitch
Article 01 Apr 2001
A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation

Simon P. Hogan
Anil Mishra
Marc E. Rothenberg
Article 01 Apr 2001
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Maria Rescigno
Matteo Urbano
Paola Ricciardi-Castagnoli
Article 01 Apr 2001

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Correction

Correction: Dysregulation of CD30⁺ T cells by leukemia impairs isotype switching in normal B cells

Correction 01 Apr 2001

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Volume 2 Issue 4, April 2001

Editorial

Peer-to-peer

Correspondence

Trouble with peer review

CTLA-4 up-regulation plays a role in tolerance mediated by CD45

Commentary

Autoimmunity versus horror autotoxicus: The struggle for recognition

News & Views

Policing the regulators

Chemokines: Not just leukocyte chemoattractants in the promotion of cancer

Extolling the diversity of bacterial endotoxins

Periscope, up! Monitoring microbes in the intestine

Round-up

Immunology highlights from the recent literature

Review Article

A fresh look at tumor immunosurveillance and immunotherapy

Article

Thymic selection of CD4⁺CD25⁺ regulatory T cells induced by an agonist self-peptide

Defining the specific physiological requirements for c-Myc in T cell development

Gene regulation mediated by calcium signals in T lymphocytes

A point mutation in CD28 distinguishes proliferative signals from survival signals

Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity

A CD14-independent LPS receptor cluster

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Correction

Correction: Dysregulation of CD30⁺ T cells by leukemia impairs isotype switching in normal B cells

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