Collections

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    An overview, four review articles and two perspective articles cover the cellular and molecular mechanisms required to maintain self tolerance, as well as events that can precipitate tolerance breakdown and lead to autoimmunity.

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    An overview, three review articles and two perspective articles cover the complex interplay among signaling pathways operative in immune cells.

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    Immune cells are constantly in motion in surveillance for potential microbial threats. Here we present a collection of reviews that describe the trafficking patterns, cues and means by which immune cells transit tissues in health and in response to infections.

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    An overview, two review articles, two perspective articles and one personal essay discuss the differentiation, responsiveness and biological functions of natural killer cells.

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    A comprehensive overview of pathogenesis: seven specially commissioned articles discuss host-pathogen encounters from several angles, with special emphasis on immune outcomes.

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    An overview, three review articles and two personal essays discuss the identification and function of transcription factors that regulate the differentiation of lymphocyte lineages.

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    A comprehensive overview and four review articles discuss the functions of plant and animal innate immune system receptors in the context of pathogen recognition and other immune functions.

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    Five especially commissioned articles that discuss how immune cells communicate in selected tissue microenvironments.

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    A comprehensive overview, and three review articles examine how inflammation is dampened by the immune system.

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    To celebrate our 5 years of serving the immunology community, we have assembled a collection of papers that illustrates the breadth of subject matter our pages cover.

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    Four review articles and a perspective examine the biology and function of regulatory T cells.