Commentary in 2006

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  • Successful microarray experimentation can generate enormous amounts of data, potentially very rich but also very unwieldy. Bold outlooks and new methods for data analysis and presentation should yield additional insight into the complexities of the immune system.

    • Gordon Hyatt
    • Rachel Melamed
    • Christophe Benoist
    Commentary
  • RNA interference and chromatin immunoprecipitation are now firmly established as useful methods for studying mechanisms of gene regulation in vivo. Their combined use can help elucidate gene regulation 'logic' by aiding in target gene identification for transcription factors and chromatin-modifying complexes.

    • Caiyi C Li
    • Vladimir R Ramirez-Carrozzi
    • Stephen T Smale
    Commentary
  • Disease-oriented, introductory medical curricula can help overcome educational and institutional barriers that separate aspiring translational scientists in PhD programs from the world of medicine.

    • Robert Busch
    • Belinda Byrne
    • Elizabeth D Mellins
    Commentary