Commentary

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  • If research and technology are to become the driving force for turning Greece into a productive society, evidence-based governance, strategic restructuring of infrastructure and a substantial inflow of fresh human capital is urgently needed.

    • George Kollias
    • John D Lambris
    Commentary
  • Advances in human genomics, when validated functionally, can lead to new insights into how the immune system works. Notably, previously unknown mechanisms revealed by genomics can lead to the development of precision medicine unanticipated on the basis of phenotype alone.

    • Yu Zhang
    • Helen C Su
    • Michael J Lenardo
    Commentary
  • Everyone and everything seems to go 'big data' these days. The task ahead will be to train young immunologists to formulate intelligent hypotheses using big data resources.

    • Joachim L Schultze
    Commentary
  • Women are underrepresented in the science and engineering fields. Difficulties in balancing family life and work have a big role in women's opting out of scientific career paths. Institutions and funding agencies need to work harder to reverse this disparity.

    • Akiko Iwasaki
    Commentary
  • Genetic, environmental and socioeconomic factors render humanity remarkably diverse. '-Omic' and sensor technologies permit the capture of this diversity with unprecedented precision. Leveraging these technologies in clinical decision making will help to bring about the long-heralded personalization of medicine.

    • Damien Chaussabel
    • Bali Pulendran
    Commentary
  • There are clear epidemiological links between nutrition and immunological function, but a dearth of mechanistic insights has made this topic controversial. Veldhoen and Veiga-Fernandes discuss this controversy and explore ways to take this research forward.

    • Marc Veldhoen
    • Henrique Veiga-Fernandes
    Commentary
  • Physician scientists bridge the gap between biomedical research and clinical practice. However, the continuing decrease in number of people who choose this career path poses a threat to the advancement of biomedical science and the translation of research findings to clinical practice.

    • Penelope A Morel
    • Gillian Ross
    Commentary
  • A workshop organized by the Society for Leukocyte Biology offers advice to graduate students on how to navigate educational and professional waters to find success in academia.

    • Michael M Chen
    • Anita Zahs
    • Elizabeth J Kovacs
    Commentary
  • It is not enough to be a good scientist. One needs to be a good communicator. When publications are clear and a pleasure to read, they will advance both the field and the authors' reputation.

    • James C Gould
    • Rafael E Luna
    • Donna L Vogel
    Commentary
  • Technological advances in antigen discovery, genomics and immunological monitoring offer tremendous potential for revolutionizing vaccine development. On 5–6 February 2014, 35 leading vaccine scientists met to consider how best to harness these advances and spur innovation.

    • Wayne C Koff
    • Ian D Gust
    • Stanley A Plotkin
    Commentary
  • Proteomics based on high-resolution mass spectrometry has become a powerful tool for the analysis of protein abundance, modifications and interactions. Here we describe technical aspects of proteomics workflows, instrumentation as well as computational considerations to obtain high-quality proteomics data.

    • Felix Meissner
    • Matthias Mann
    Commentary
  • To overcome the limitations of seasonal influenza virus vaccines and enhance our pandemic preparedness, influenza virus vaccines that provide universal and long-lasting protection are needed.

    • Florian Krammer
    • Peter Palese
    Commentary
  • Successful interviewing can be best attributed to a combination of careful research and preparation, along with the ability to connect with employers on a personal level and demonstrate value.

    • Derek Haseltine
    • James Gould
    Commentary