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Emerging technologies are broadening our understanding of the human immune system, but capitalizing on their application will likely require philosophical and practical changes to the way research is done.
Evolutionarily shaped molecular and cellular interactions between bacterial commensals and the host immune system drive a mutually beneficial relationship.
The multiprotein inflammasome complexes are important in responses to microbes but are also increasingly recognized as having key pathogenic roles in a variety of diseases from cancer to obesity.
Memory is the signature property of the adaptive response, and vaccination is a hugely important medical intervention—understanding the former will help perfect the latter.
Nature Immunology launches its first podcast with a historical piece on immunology at the UK's National Institute of Medical Research as plans develop for the future of the institute.
Against a backdrop of some of the most savage spending cuts in the developed world, the UK science budget has emerged relatively unscathed, but funding priorities may yet prove problematic.