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  • Stromal-immune cell interactions

    Please see the Nature Portfolio Collection on Stromal–Immune Cell Interactions. You will find recent research articles and reviews that discuss the players and factors involved in stromal–immune cell interactions in both health and disease.

  • Many mentors

    Please see the Nature Portfolio Collection on Mentorship, presenting a series of commissioned World Views and Comments by authors who speak about how they view their roles as mentors and how to improve mentorship.

  • SARS-CoV-2 virions

    Nature Immunology has commissioned a Focus series of Reviews and Perspectives that discuss the innate and adaptive aspects of the immune response to SARS-CoV2, the possible mechanisms behind the large clinical variability in the response to infection, and considerations for vaccine and therapy strategies.

Nature Immunology is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.

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    • Akin to adult stem cells, precursor exhausted T cells are hierarchically organized, with long-lived CD62L+ stem-like T cells at the apex of the system. The transcription factor c-Myb controls the formation, maintenance and therapeutic function of these cells, with important implications for their clinical utilization.

      • Christoph Heuser
      • Luca Gattinoni
      News & Views
    • Current SARS-CoV-2 vaccine recipients differ in infection history and the magnitude of their elicited antibody response. A large human cohort distinguished by these parameters are queried for effector T cell subsets, memory B cells and ability to recognize epitopes from SARS-CoV-2 variants of concern.

      • Andrea J. Sant
      • Patrick C. Wilson
      News & Views
    • m1A58 is a common tRNA modification that can influence protein translational efficiency. Here Liu et al. reveal that tRNA methylation controls in vivo T cell activation by enhancing translation of the key transcription factor Myc.

      • Julia M. Marchingo
      News & Views
    • On 3–8 June 2022, the First International Aegean Conference on Mesenchymal Cells in Health & Disease took place in Chania, Crete, and brought together clinicians and scientists who work on mesenchymal or stromal cell biology across different fields including immunity, inflammation and cancer.

      • Vasiliki Koliaraki
      • Gian-Paolo Dotto
      • George Kollias
      Meeting Report
    • Immunotherapeutic targeting of the surface glycoprotein CD19 has markedly improved outcomes in patients with relapsed and refractory B cell progenitor acute lymphoblastic leukemia. Genome-wide CRISPR–Cas9 screening identifies modulators of CD19 mRNA processing that affect the abundance of the surface protein in human B cell leukemia cells, with the potential to improve antigen-directed immunotherapy efficacy.

      Research Briefing

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