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A microbial iron fist to fight tumors
The microbiome is known to affect antitumor immune responses, but how this occurs is unclear. Rhamnose-rich polysaccharides (RHP) from a commensal strain of Lactiplantibacillus plantarum have now been shown to induce iron sequestration by tumor macrophages, thereby limiting tumor growth and promoting antitumor immunity.
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Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection
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SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
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Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins
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JAK-STAT signaling maintains homeostasis in T cells and macrophages