Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 43 Issue 2, February 2011

Cover art by Erin Dewalt

Volume 43 Issue 2

Editorial

  • As genome sequencing becomes more versatile and easier, the journal prioritizes those genomic sequences that maximize the prospects of harnessing genome variation and understanding evolutionary processes.

    Editorial

    Advertisement

Top of page ⤴

News & Views

  • Two studies illustrate that with the appropriate resources and scale of study, most of the heritability of complex traits in maize is not missing, but can be located within the genome. Given that maize is one of the world's most important crop plants, this has implications for feeding a growing population with minimum carbon footprint as well as for understanding the genetics of complex traits in a range of species.

    • Chris Haley
    News & Views
  • A new study shows that the piRNA-binding protein Piwi interacts with Hsp90 and suppresses phenotypic variation in Drosophila melanogaster by preventing the expression of hidden epigenetic variation. This suggests that Hsp90 and Piwi function are dampened in times of stress to increase genetic and epigenetic variability, providing a last-ditch mechanism for a species to survive.

    • Douglas M Ruden
    News & Views
  • Two new studies show that mutations in tartrate-resistant acid phosphatase (TRAP) cause spondyloenchondrodysplasia, a rare recessive disease associated with short stature, brain calcifications and lupus-like autoimmunity. The complex clinical syndrome is probably mediated by impaired dephosphorylation of osteopontin.

    • Timothy W Behrens
    • Robert R Graham
    News & Views
Top of page ⤴

Research Highlights

Top of page ⤴

Analysis

  • Johan Paulsson and Dann Huh report a mathematical modeling analysis proposing that stochastic partitioning errors during cell division contribute to non-genetic heterogeneity between cells in a population. They find that fluctuations arising from such partitioning errors are difficult to suppress and can mimic noise in gene expression.

    • Dann Huh
    • Johan Paulsson
    Analysis
Top of page ⤴

Article

  • Xavier Argout and colleagues report the draft genome of Theobroma cacao, the tropical crop that is the source of chocolate. The sequence assembly covers approximately 80% of the genome.

    • Xavier Argout
    • Jerome Salse
    • Claire Lanaud
    Article Open Access
  • The International Strawberry Sequencing Consortium reports the draft genome of the woodland strawberry (Fragaria vesca). The genome of this diploid species should serve as a reference genome for the Fragaria genus, as the cultivated strawberry (Fragaria × ananassa) is an octoploid where F. vesca is predicted to be a subgenome donor.

    • Vladimir Shulaev
    • Daniel J Sargent
    • Kevin M Folta
    Article Open Access
Top of page ⤴

Letter

Top of page ⤴

Search

Quick links