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Volume 40 Issue 3, March 2008

Cover art: Coiled Forms and Shadows By Linda Rahl Nadashttp://www.lindarahlnadas.com

Volume 40 Issue 3

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Editorial

  • Three genome-wide association studies of prostate cancer deliver a mix of newly identified associations, tripling the available number of candidate genes, biomarkers and variants potentially useful in risk prediction.

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Correspondence

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News & Views

  • Rare syndromes offer unique opportunities to gain insight into central physiological processes. By deciphering the genetic basis of two rare inherited diseases, two studies identify a key role for P2Y5, a G protein–coupled receptor, in hair follicle development.

    • Eli Sprecher
    News & Views

  • During meiosis, crossovers are regulated such that each pair of chromosomes has at least one crossover and multiple crossovers are evenly spaced. A new study leads to surprising insights regarding the timing of crossover regulation through the analysis of two genes involved in synaptonemal complex elongation.

    • Luke E Berchowitz
    • Gregory P Copenhaver
    News & Views

  • Cranial neural crest cell migration is a prerequisite for normal craniofacial morphogenesis in animals. A new study shows that the movement of a specific subset of cranial neural crest cells is exquisitely sensitive to concentrations of a microRNA that targets platelet-derived growth factor receptor alpha mRNA.

    • David E Clouthier
    News & Views

  • A new mapping study identifies a natural protein variant influencing oil content and composition in maize seeds. This example illustrates the power of exploiting natural variation to improve crop yields and address current breeding challenges.

    • Dani Zamir
    News & Views
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Perspective

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Brief Communication

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Article

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Letter

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Corrigendum

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