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Volume 39 Issue 12, December 2007

Cover Art: Array of Pigment by Erin Boyle. Original concept by Jón Gústafsson jon.gustafsson@decode.is

Volume 39 Issue 12

Editorial

  • Recent discoveries and improvements in technology have boosted the profile of 'personalized genomics'. But the demonstrated complexities of the genetics of common disease suggest caution—and an urgent need for more data, both in and out of the lab.

    Editorial

    Advertisement

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Obituary

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Book Review

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News & Views

  • This is an issue edsumm for 1421. Identification of the Palaeocene/Eocene thermal maximum in a marine sedimentary sequence shows that sea surface temperatures near the North Pole increased from roughly 18 degrees Celsius to over 23 degrees Celsius — such warm values imply the absence of ice and thus exclude the influence of ice-albedo feedbacks on this Arctic warming.

    • John W Tamkun
    News & Views
  • This is an issue edsumm for 1422. Identification of the Palaeocene/Eocene thermal maximum in a marine sedimentary sequence shows that sea surface temperatures near the North Pole increased from roughly 18 degrees Celsius to over 23 degrees Celsius — such warm values imply the absence of ice and thus exclude the influence of ice-albedo feedbacks on this Arctic warming.

    • Rudi Balling
    News & Views
  • Lipoprotein lipase, the enzyme that hydrolyzes fatty acids from triglycerides carried by circulating lipoproteins, resides on the surface of the capillary endothelium. Analysis of a hypertriglyceridemic mutant mouse has now identified a protein, LMF1, that is critical for the transport of active lipoprotein lipase through the secretory pathway.

    • Alan D Attie
    News & Views
  • Dramatically different mutant phenotypes usually reflect mutations in different genes, but this is not necessarily so, especially when microRNA regulation is involved. A beautiful example of this now comes from the discovery of the maize microRNA tasselseed4 and its target ids1/Tasselseed6, which uncovers a new facet in the control of inflorescence branching and sex determination in flowers.

    • Andrea Gallavotti
    • Robert J Schmidt
    News & Views
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Brief Communication

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Article

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Letter

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Technical Report

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Erratum

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