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SPRTN is a new player in an old story

Nature Genetics volume 46, pages 1155–1157 (2014)Cite this article

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A Corrigendum to this article was published on 30 December 2014

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A new study identifies rare mutations in SPRTN that cause a novel progeroid syndrome. The results point to an unexpected function of SPRTN and bring insight to the mechanisms that link premature aging and cancer.

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Figure 1: The dual roles of SPRTN.

Katie Vicari/Nature Publishing Group

Change history

  • 12 November 2014

    In the version of this article initially published, a sentence on page 1156 stated, "This disease was named SPRTN syndrome," in reference to the genetic syndrome described by Lessel et al. (Nat. Genet. 46, 1239–1244, 2014). However, the article by Lessel et al. did not propose a name for the new syndrome. The error has been corrected in the HTML and PDF versions of the article.

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  1. Kevin Hiom is at Ninewells Medical School and Hospital, University of Dundee, Dundee, UK.,

    Kevin Hiom

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  1. Kevin Hiom
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Correspondence to Kevin Hiom.

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Hiom, K. SPRTN is a new player in an old story. Nat Genet 46, 1155–1157 (2014). https://doi.org/10.1038/ng.3125

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