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Closing in on complex traits

Nature Genetics volume 38, pages 861–862 (2006)Cite this article

A new study involving a population of 1,904 heterogeneous mice bred for 50 generations, phenotyped for 101 traits and genotyped for 13,459 SNPs, presents the most comprehensive analysis thus far of complex traits in mice. The work represents a landmark resource for the mouse genetics community and offers important insights into the genetic architecture of complex traits.

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Figure 1: Heterogeneous stock mice (illustrated in this picture) helped Valdar et al. detect 843 QTLs.

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  1. Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel

    Ariel Darvasi

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  1. Ariel Darvasi
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Darvasi, A. Closing in on complex traits. Nat Genet 38, 861–862 (2006). https://doi.org/10.1038/ng0806-861

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