Collections

  • Collection |

    One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.

    Image: Nicolas Plachta, NCB (2022)
  • Collection |

    Research interest is growing in profiling noncoding RNAs and understanding their biological functions in health and disease contexts.

    Image: Jeren (France) / Getty Images
  • Collection |

    The 2022 Nobel Prize in Physiology or Medicine was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution".

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Collection |

    Gregor Johann Mendel, considered by many the ‘father of modern genetics’, was born 200 years ago, on 20 July 1822.

    Image: P. Morgan, Springer Nature
  • Collection |

    Recent technological progress has facilitated the study of how embryos develop, how embryonic cells transition between different states, how adult stem cells are maintained and differentiate, at unprecedented resolution.

    Image: Deepti L Kumar and Tony DeFalco
  • Special |

    Genome Engineering has great potential to change how we model, understand, and treat diseases.

    Image: XVIVO
  • Milestone |

    The past two decades have witnessed extraordinary technological and computational advances in nucleic acid sequencing. This Milestone timeline provides a perspective of major genomic sequencing-related developments in the 21st century — from the first human reference genome, through methodological breakthroughs, to the impact of sequencing on fields as diverse as microbiology, cancer and palaeogenetics.

    Image: Chris Ryan
  • Milestone |

    The ancient physician Hippocrates described the projection of blood vessels from a collection of cells as ‘karkinos’, the Greek word for crab.

    Image: Chris Ryan
  • Collection |

    This collection of research, review and comment from Nature Research celebrates the 2020 Nobel Prize in Physiology or Medicine awarded to Harvey J. Alter, Michael Houghton and Charles M. Rice "for the discovery of hepatitis C virus".

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Special |

    How cells, tissues and organisms interpret the information encoded in the genome has vital implications for our understanding of development, health and disease. Launched in 2003, the ENCyclopedia of DNA Elements (ENCODE) project aims to map the functional elements in the human genome (later expanded to include model organisms).

    Image: StoryTK
  • Collection |

    New technologies to study stem cells have increased our knowledge about their physiological roles and contributions to development, ageing, regeneration and disease. This collection showcases research articles, reviews and protocols from across the Nature journals to highlight the striking advances made in basic and translational stem cell research.

    Image: Benedetta Artegiani and Delilah Hendriks, Hubrecht Institute, Utrecht, The Netherlands.
  • Special |

    Cancers evolve at a dynamic pace to adapt to immune pressure, colonize new niches, and evade therapy. Tracking these changes can help us improve diagnosis, better tailor therapies, and forestall recurrence, but it requires intensive monitoring beyond current clinical practice.

    Image: Jeroen Claus / Phospho Biomedical Animation