Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Zhiwu Zhang and colleagues report a mixed linear model approach for correcting for population structure and family relatedness in genome-wide association studies.
Eleazar Eskin and colleagues report a variance component model for correcting for sample structure in association studies. The EMMAX program is publicly available and may be used for analysis of genome-wide association study datasets.