Spatial resolution of pancreatic cancer

Spatial resolution of pancreatic cancer

Single-nucleus and spatial transcriptomics analyses of human pancreatic cancer provide insights into cell populations and cell states associated with the disease.

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  • Many large research initiatives have cumulatively enrolled thousands of patients with a range of complex medical issues but no clear genetic etiology. However, it is unclear how researchers, institutions and funders should manage the data and relationships with those participants who remain undiagnosed when these studies end. In this Comment, we outline the current literature relevant to post-study obligations in clinical genomics research and discuss the application of current guidelines to research with undiagnosed participants.

    • Meghan C. Halley
    • Euan A. Ashley
    • Holly K. Tabor
    Comment
  • In this issue of Nature Genetics, we celebrate the legacy of Gregor Mendel, who was born 200 years ago. We also note the 30th anniversary of the launch of Nature Genetics. The convergence of these two milestones helps us to look back on how far the genetics field has come, and also to look to the future to see where we are heading.

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