Yuxian Liu and Wei Yao

Sugarcane genome

Latest Research

  • Letter |

    In zebrafish, cilia-driven flow of cerebrospinal fluid transports adrenergic signals that induce urotensin neuropeptides in spinal cord neurons. In turn, these neuropeptides activate their receptor on nearby muscle fibers, straightening the body axis.

    • Xiaoli Zhang
    • , Shuo Jia
    • , Zhe Chen
    • , Yan Ling Chong
    • , Haibo Xie
    • , Dong Feng
    • , Xiaotong Wu
    • , Don Zhu Song
    • , Sudipto Roy
    •  & Chengtian Zhao
  • Article |

    Integrated analysis of transcriptome, open chromatin region and chromatin conformation capture data from subjects with acute myeloid leukemia (AML) harboring defined transcription factor and signaling molecule alterations provide insights into the subtype-specific regulatory network in AML.

    • Salam A. Assi
    • , Maria Rosaria Imperato
    • , Daniel J. L. Coleman
    • , Anna Pickin
    • , Sandeep Potluri
    • , Anetta Ptasinska
    • , Paulynn Suyin Chin
    • , Helen Blair
    • , Pierre Cauchy
    • , Sally R. James
    • , Joaquin Zacarias-Cabeza
    • , L. Niall Gilding
    • , Andrew Beggs
    • , Sam Clokie
    • , Justin C. Loke
    • , Phil Jenkin
    • , Ash Uddin
    • , Ruud Delwel
    • , Stephen J. Richards
    • , Manoj Raghavan
    • , Michael J. Griffiths
    • , Olaf Heidenreich
    • , Peter N. Cockerill
    •  & Constanze Bonifer
  • Article |

    Analysis of genotyping-by-sequencing data for more than 20,000 barley accessions from a German genebank provides a framework for genomics-assisted genebank management and analysis of large germplasm collections for important crops.

    • Sara G. Milner
    • , Matthias Jost
    • , Shin Taketa
    • , Elena Rey Mazón
    • , Axel Himmelbach
    • , Markus Oppermann
    • , Stephan Weise
    • , Helmut Knüpffer
    • , Martín Basterrechea
    • , Patrick König
    • , Danuta Schüler
    • , Rajiv Sharma
    • , Raj K. Pasam
    • , Twan Rutten
    • , Ganggang Guo
    • , Dongdong Xu
    • , Jing Zhang
    • , Gerhard Herren
    • , Thomas Müller
    • , Simon G. Krattinger
    • , Beat Keller
    • , Yong Jiang
    • , Maria Y. González
    • , Yusheng Zhao
    • , Antje Habekuß
    • , Sandra Färber
    • , Frank Ordon
    • , Matthias Lange
    • , Andreas Börner
    • , Andreas Graner
    • , Jochen C. Reif
    • , Uwe Scholz
    • , Martin Mascher
    •  & Nils Stein
  • Technical Report |

    A machine learning approach for refinement of somatic variant calls automates this process and reduces bias stemming from inter-reviewer variability.

    • Benjamin J. Ainscough
    • , Erica K. Barnell
    • , Peter Ronning
    • , Katie M. Campbell
    • , Alex H. Wagner
    • , Todd A. Fehniger
    • , Gavin P. Dunn
    • , Ravindra Uppaluri
    • , Ramaswamy Govindan
    • , Thomas E. Rohan
    • , Malachi Griffith
    • , Elaine R. Mardis
    • , S. Joshua Swamidass
    •  & Obi L. Griffith
  • Article | | open

    Comparative study of 81 genomes of parasitic and non-parasitic worms identifies gene family births and expanded gene families at key nodes in the phylogeny that are relevant to parasitism and proteins historically targeted for drug development.

    • Avril Coghlan
    • , Rahul Tyagi
    • , James A. Cotton
    • , Nancy Holroyd
    • , Bruce A. Rosa
    • , Isheng Jason Tsai
    • , Dominik R. Laetsch
    • , Robin N. Beech
    • , Tim A. Day
    • , Kymberlie Hallsworth-Pepin
    • , Huei-Mien Ke
    • , Tzu-Hao Kuo
    • , Tracy J. Lee
    • , John Martin
    • , Rick M. Maizels
    • , Prudence Mutowo
    • , Philip Ozersky
    • , John Parkinson
    • , Adam J. Reid
    • , Neil D. Rawlings
    • , Diogo M. Ribeiro
    • , Lakshmipuram Seshadri Swapna
    • , Eleanor Stanley
    • , David W. Taylor
    • , Nicolas J. Wheeler
    • , Mostafa Zamanian
    • , Xu Zhang
    • , Fiona Allan
    • , Judith E. Allen
    • , Kazuhito Asano
    • , Simon A. Babayan
    • , Germanus Bah
    • , Helen Beasley
    • , Hayley M. Bennett
    • , Stewart A. Bisset
    • , Estela Castillo
    • , Joseph Cook
    • , Philip J. Cooper
    • , Teresa Cruz-Bustos
    • , Carmen Cuéllar
    • , Eileen Devaney
    • , Stephen R. Doyle
    • , Mark L. Eberhard
    • , Aidan Emery
    • , Keeseon S. Eom
    • , John S. Gilleard
    • , Daria Gordon
    • , Yvonne Harcus
    • , Bhavana Harsha
    • , John M. Hawdon
    • , Dolores E. Hill
    • , Jane Hodgkinson
    • , Petr Horák
    • , Kevin L. Howe
    • , Thomas Huckvale
    • , Martin Kalbe
    • , Gaganjot Kaur
    • , Taisei Kikuchi
    • , Georgios Koutsovoulos
    • , Sujai Kumar
    • , Andrew R. Leach
    • , Jane Lomax
    • , Benjamin Makepeace
    • , Jacqueline B. Matthews
    • , Antonio Muro
    • , Noel Michael O’Boyle
    • , Peter D. Olson
    • , Antonio Osuna
    • , Felix Partono
    • , Kenneth Pfarr
    • , Gabriel Rinaldi
    • , Pilar Foronda
    • , David Rollinson
    • , Mercedes Gomez Samblas
    • , Hiroshi Sato
    • , Manuela Schnyder
    • , Tomáš Scholz
    • , Myriam Shafie
    • , Vincent N. Tanya
    • , Rafael Toledo
    • , Alan Tracey
    • , Joseph F. Urban
    • , Lian-Chen Wang
    • , Dante Zarlenga
    • , Mark L. Blaxter
    • , Makedonka Mitreva
    •  & Matthew Berriman
  • Article |

    Whole-genome sequencing of 175 Mongolians representing six tribes highlights population-specific genetic architecture and substantial gene flow among northern Eurasian populations, including derived alleles shared by Mongolians and Finns.

    • Haihua Bai
    • , Xiaosen Guo
    • , Narisu Narisu
    • , Tianming Lan
    • , Qizhu Wu
    • , Yanping Xing
    • , Yong Zhang
    • , Stephen R. Bond
    • , Zhili Pei
    • , Yanru Zhang
    • , Dandan Zhang
    • , Jirimutu Jirimutu
    • , Dong Zhang
    • , Xukui Yang
    • , Morigenbatu Morigenbatu
    • , Li Zhang
    • , Bingyi Ding
    • , Baozhu Guan
    • , Junwei Cao
    • , Haorong Lu
    • , Yiyi Liu
    • , Wangsheng Li
    • , Ningxin Dang
    • , Mingyang Jiang
    • , Shenyuan Wang
    • , Huixin Xu
    • , Dingzhu Wang
    • , Chunxia Liu
    • , Xin Luo
    • , Ying Gao
    • , Xueqiong Li
    • , Zongze Wu
    • , Liqing Yang
    • , Fanhua Meng
    • , Xiaolian Ning
    • , Hashenqimuge Hashenqimuge
    • , Kaifeng Wu
    • , Bo Wang
    • , Suyalatu Suyalatu
    • , Yingchun Liu
    • , Chen Ye
    • , Huiguang Wu
    • , Kalle Leppälä
    • , Lu Li
    • , Lin Fang
    • , Yujie Chen
    • , Wenhao Xu
    • , Tao Li
    • , Xin Liu
    • , Xun Xu
    • , Christopher R. Gignoux
    • , Huanming Yang
    • , Lawrence C. Brody
    • , Jun Wang
    • , Karsten Kristiansen
    • , Burenbatu Burenbatu
    • , Huanmin Zhou
    •  & Ye Yin

News & Comment

  • News & Views |

    A new study identifies loss-of-function mutations in HAVCR2, which encodes TIM-3, in patients with a rare cutaneous T cell lymphoma associated with aberrant immunological activation. These mutations lead to loss of the TIM-3 immunological checkpoint, thus promoting inflammation and malignancy.

    • Karen O. Dixon
    • , Madhumita Das
    •  & Vijay K. Kuchroo
  • Correspondence |

    • Maxime Tarabichi
    • , Iñigo Martincorena
    • , Moritz Gerstung
    • , Armand M. Leroi
    • , Florian Markowetz
    • , Stefan C. Dentro
    • , Ignaty Leshchiner
    • , Moritz Gerstung
    • , Clemency Jolly
    • , Kerstin Haase
    • , Maxime Tarabichi
    • , Jeff Wintersinger
    • , Amit G. Deshwar
    • , Kaixian Yu
    • , Santiago Gonzalez
    • , Yulia Rubanova
    • , Geoff Macintyre
    • , David J. Adams
    • , Pavana Anur
    • , Rameen Beroukhim
    • , Paul C. Boutros
    • , David D. Bowtell
    • , Peter J. Campbell
    • , Shaolong Cao
    • , Elizabeth L. Christie
    • , Marek Cmero
    • , Yupeng Cun
    • , Kevin J. Dawson
    • , Jonas Demeulemeester
    • , Nilgun Donmez
    • , Ruben M. Drews
    • , Roland Eils
    • , Yu Fan
    • , Matthew Fittall
    • , Dale W. Garsed
    • , Gad Getz
    • , Gavin Ha
    • , Marcin Imielinski
    • , Lara Jerman
    • , Yuan Ji
    • , Kortine Kleinheinz
    • , Juhee Lee
    • , Henry Lee-Six
    • , Dimitri G. Livitz
    • , Salem Malikic
    • , Florian Markowetz
    • , Iñigo Martincorena
    • , Thomas J. Mitchell
    • , Ville Mustonen
    • , Layla Oesper
    • , Martin Peifer
    • , Myron Peto
    • , Benjamin J. Raphael
    • , Daniel Rosebrock
    • , S. Cenk Sahinalp
    • , Adriana Salcedo
    • , Matthias Schlesner
    • , Steven Schumacher
    • , Subhajit Sengupta
    • , Ruian Shi
    • , Seung Jun Shin
    • , Lincoln D. Stein
    • , Ignacio Vázquez-García
    • , Shankar Vembu
    • , David A. Wheeler
    • , Tsun-Po Yang
    • , Xiaotong Yao
    • , Ke Yuan
    • , Hongtu Zhu
    • , Wenyi Wang
    • , Quaid D. Morris
    • , Paul T. Spellman
    • , David C. Wedge
    • , Peter Van Loo
    • , Paul T. Spellman
    • , Quaid D. Morris
    • , Ole Christian Lingjærde
    • , David C. Wedge
    •  & Peter Van Loo
  • Correspondence |

    • Timon Heide
    • , Luis Zapata
    • , Marc J. Williams
    • , Benjamin Werner
    • , Giulio Caravagna
    • , Chris P. Barnes
    • , Trevor A. Graham
    •  & Andrea Sottoriva
  • Correspondence |

    • Lars A. Forsberg
    • , Jonatan Halvardson
    • , Edyta Rychlicka-Buniowska
    • , Marcus Danielsson
    • , Behrooz Torabi Moghadam
    • , Jonas Mattisson
    • , Chiara Rasi
    • , Hanna Davies
    • , Lars Lind
    • , Vilmantas Giedraitis
    • , Lars Lannfelt
    • , Lena Kilander
    • , Martin Ingelsson
    •  & Jan P. Dumanski

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