Volume 9 Issue 11, November 2006

Volume 9 Issue 11

Many neurons in cortical area MT are selective for the motion of complex patterns, independent of their component orientations. Rust and colleagues now propose a new model that predicts these neuronal responses based on previously described properties of neurons in primary visual cortex. The cover shows a contour map representing the responses of a pattern-selective neuron in macaque MT to the set of moving gratings and plaids shown in the background. (pp 1356 and 1421)


Book Review

News and Views

  • News & Views |

    How do neurons combine separate pieces of information that are only partially reliable? Surprisingly, their noise properties may simplify the underlying computations while allowing them to maintain optimal performance.

    • Emilio Salinas
  • News & Views |

    An inhibitor of glycolysis is shown to have antiepileptic effects in the rat kindling model, possibly through NADH-dependent regulation of gene expression. This may explain how the 'ketogenic diet' treatment works.

    • Yang Zhong Huang
    •  & James O McNamara
  • News & Views |

    Glutamate transporters have long been thought to help terminate the synaptic response through neurotransmitter binding and reuptake, but a new report in this issue identifies a role for their anionic current in information transmission in the retina.

    • Jacques I Wadiche
    •  & Henrique von Gersdorff
  • News & Views |

    Most early-onset familial Alzheimer disease is caused by presenilin mutations. A recent paper reports that the presenilins act as calcium leak channels in the endoplasmic reticulum and thus may regulate intracellular calcium homeostasis.

    • Gopal Thinakaran
    •  & Sangram S Sisodia
  • News & Views |

    Multiple local motions must be combined to determine the direction of object motion, which is harder than it seems. A new paper proposes an elegant and simple solution to this problem, eminently realizable in feed-forward circuits.

    • Tao Zhang
    •  & Kenneth H Britten

Brief Communications