Volume 3 Issue 5, May 2000

Volume 3 Issue 5

The cover shows an embryonic hippocampal neuron transfected with VAMP–GFP. Individual images in a time series are coded in different colors and overlaid, demonstrating that elements of the presynaptic active zone move down the axon together in cytoplasmic transport packets. See pages 415 and 445.


Letters to Editor

News and Views

  • News & Views |

    A morphological study suggests a new view of synapse formation by demonstrating that presynaptic elements are assembled into ‘prototerminals’ before being transported down axons by fast, saltatory movement. These structures stop moving when the axon contacts a dendrite.

    • Jack Roos
    •  & Regis B. Kelly
  • News & Views |

    A new study shows that sodium channels interact with receptor-like tyrosine phosphatase β, which increases sodium currents and may also help localize the channels.

    • Michael W. Salter
    •  & Yu Tian Wang
  • News & Views |

    A sophisticated study of error-related brain potentials in patients with prefrontal lesions addresses how we monitor performance and adjust cognitive control based on task demands.

    • Jonathan D. Cohen
    • , Matthew Botvinick
    •  & Cameron S. Carter
  • News & Views |

    The full sequence of the Drosophila genome is now available. A comparison with other genomes promises to yield many new insights into how genes control neural development and function.

    • George L. Gabor Miklos
    •  & Ryszard Maleszka

Book Review

Brief Communications