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Volume 23 Issue 1, January 2020

Volume 23 Issue 1

Somatostatin and affective state discrimination

Scheggia, Managò and colleagues describe a specific subpopulation of somatostatin-expressing cortical neurons that has a primary role in orchestrating the ability of mice to discriminate positive and negative affective states in their conspecifics. This finding is artistically depicted on the cover, which shows a somatostatin interneuron lighting up a stressed and a relieved mouse, but not another with neutral affect. This fundamental social cognitive ability is crucial for daily life exploration of the world and the quality of social interactions.

See Scheggia et al.

Image credit: Ella Maru Studio. Cover design: Marina Corral Spence

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