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Volume 22 Issue 12, December 2019

Volume 22 Issue 12

Trace cells in human entorhinal cortex

Episodic memory requires binding of memory content with the context in which the memory was experienced. In this issue, Qasim et al. report on how this process might be supported by specific cells in the human medial temporal lobe. In particular, they find memory-trace cells in the entorhinal cortex that, in a spatial memory task, encode the location that subjects associate with the specific memory they are required to retrieve. The cover art depicts a pool of water representing all of a person’s memories. That person is seen reaching towards a particular memory that is bound to its spatial context, characterized here by buildings, objects and landmarks arranged in space.

See Qasim et al.

Image credit: Jasu Hu. Cover design: Marina Corral Spence

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