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This Resource paper describes a set of five new reporter mice, derived from Rosa26, driving Cre-dependent strong and ubiquitous expression of fluorescent proteins. In particular, the new mice show clear and specific expression patterns in the adult brain. The mice are available through Jackson Laboratories, and growing expression datasets can be accessed at http://transgenicmouse.alleninstitute.org/.
Selective targeting of specific neuronal populations, for genetic or other manipulations, is crucial to much of neuroscience. The authors screened 536 BAC transgenic mouse lines from the GENSAT collection for specific reporter expression in the retina. Here, they describe several mouse lines selectively targeting different retinal cell types. The full dataset is accessible at http://www.gensat.org/retina.jsp.
This resource article describes a bioinformatical tool that, accessing an extensive gene expression database, allows the definition and identification of new brain structures based on gene expression patterns.
