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  • How the brain tracks blood glucose dynamics is unclear. Viskaitis et al. show that hypothalamic orexin/hypocretin cells track glucose concentration and rate of change and that their activity is important for glucose-evoked locomotor suppression.

    • Paulius Viskaitis
    • Alexander L. Tesmer
    • Denis Burdakov
    ArticleOpen Access
  • LINE-1 retrotransposons are a type of mobile DNA element normally repressed in the body. Here the authors show that LINE-1 sequences can jump in mouse parvalbumin interneurons and also promote the transcription of key parvalbumin interneuron genes.

    • Gabriela O. Bodea
    • Juan M. Botto
    • Geoffrey J. Faulkner
    ArticleOpen Access
  • The circuit mechanisms underlying emotion recognition are unclear. Here, Dautan et al. show a role for a long-range feedback loop comprising somatostatin inhibitory projections from the medial prefrontal cortex (mPFC) to the retrosplenial cortex (RSC) and excitatory feedback projections from the RSC to the mPFC.

    • Daniel Dautan
    • Anna Monai
    • Francesco Papaleo
  • Christenson et al. describe hue-selective neurons in the fruit fly optic lobe. Using a connectomics-constrained model combined with genetic manipulations of the circuit, they show that recurrent connections are critical for hue selectivity.

    • Matthias P. Christenson
    • Alvaro Sanz Diez
    • Rudy Behnia
    ArticleOpen Access
  • The increased inclusion of samples from individuals from minoritized communities in biomedical research will help to mitigate health disparities that stem from a medical enterprise founded in racism and exclusion. In this issue of Nature Neuroscience, Benjamin et al. investigate how genetic ancestry influences the expression of genes in the brain, an effort supported by community leaders who raised funding, partnered in shaping research questions and had a central role in the interpretation and communication of the study’s findings. Here, we outline the public and social context that motivated these efforts towards ensuring equitable access to the benefits of science for all.

    • Kafui Dzirasa
    • Gwenaëlle E. Thomas
    • Alvin C. Hathaway Sr
  • Effective science communication is necessary for engaging the public in scientific discourse and ensuring equitable access to knowledge. Training doctoral students in science communication will instill principles of accessibility, accountability, and adaptability in the next generation of scientific leaders, who are poised to expand science’s reach, generate public support for research funding, and counter misinformation. To this aim, we provide a guide for implementing formal science communication training for doctoral students.

    • Christina Maher
    • Trevonn Gyles
    • Daniela Schiller

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