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Widespread changes in alternative splicing in developing and adult mouse brain
In the first comprehensive mRNA isoform atlas of the developing and adult mouse brain, we discover that region and age influence the isoform repertoire of cell subtypes. We link peak cell type regulation to the critical development period and report attenuated levels in adulthood.
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Pervasive environmental chemicals impair oligodendrocyte development
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Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain
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Identification of a dopamine pathway that regulates sleep and arousal in Drosophila
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Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration