Reviews & Analysis

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  • Animal ecologists are increasingly limited by constraints in data processing. Here, Tuia and colleagues discuss how collaboration between ecologists and data scientists can harness machine learning to capitalize on the data generated from technological advances and lead to novel modeling approaches.

    • Devis Tuia
    • Benjamin Kellenberger
    • Tanya Berger-Wolf
    Perspective Open Access
  • Many biological processes require changes in the physical properties of cells and their surroundings. Here, Lenne and Trivedi discuss recent findings in biological systems in terms of phase transitions in inert physical systems from both theoretical and experimental perspectives.

    • Pierre-François Lenne
    • Vikas Trivedi
    Perspective Open Access
  • Synthetic DNA is the basis for promising technologies in data storage, barcoding, computing 62 and sercurity. In this review, the authors provide an overview of the field and its future.

    • Linda C. Meiser
    • Bichlien H. Nguyen
    • Robert N. Grass
    Review Article Open Access
  • The reasons for concern framework are an effective visualisation of climate change related risks. Here, the authors propose a new framework by which different levels of uncertainty can be included into this aggregated assessment in order to ensure a transparent communication of risks.

    • Luke J. Harrington
    • Carl-Friedrich Schleussner
    • Friederike E. L. Otto
    Perspective Open Access
  • Cooperation is vulnerable to cheating, and both cooperation and cheating may be especially common in viruses. Here, Leeks et al. place diverse examples of viral cooperation and cheating within an evolutionary framework, highlighting opportunities emerging from greater synthesis of virology and evolutionary theory.

    • Asher Leeks
    • Stuart A. West
    • Melanie Ghoul
    Perspective Open Access
  • New observations of volcanic and magmatic activity in Africa are changing our views of continental rifting and raising awareness of the associated hazards. However, despite a shift from crisis response to reducing disaster risks, limited capacity means mitigating geohazards remains challenging.

    • Juliet Biggs
    • Atalay Ayele
    • Tim J. Wright
    Review Article Open Access
  • Cellular microbiology is a field that combines the study of infection and cell biology. In this review, we highlight emerging technologies and infection models that recently transformed our understanding of the infected cell and may inspire future medicine.

    • Ana Teresa López-Jiménez
    • Serge Mostowy
    Review Article Open Access
  • The number of publicly available proteomics datasets is growing rapidly, but a standardized approach for describing the associated metadata is lacking. Here, the authors propose a format and a software pipeline to present and validate metadata, and integrate them into ProteomeXchange repositories.

    • Chengxin Dai
    • Anja Füllgrabe
    • Yasset Perez-Riverol
    Perspective Open Access
  • The microbiome is becoming recognized as a key determinant of host phenotype. Here, Henry et al. present a framework for building our understanding of how the microbiome also influences host evolution, review empirical examples and research approaches, and highlight emerging questions.

    • Lucas P. Henry
    • Marjolein Bruijning
    • Julien F. Ayroles
    Perspective Open Access
  • Seed banks are generated when individuals enter a dormant state, a phenomenon that has evolved among diverse taxa, but that is also found in stem cells, brains, and tumors. Here, Lennon et al. synthesize the fundamentals of seed-bank theory and the emergence of complex patterns and dynamics in mathematics and the life sciences.

    • Jay T. Lennon
    • Frank den Hollander
    • Jochen Blath
    Review Article Open Access
  • Vast, ancient impact basins scattered mantle materials across the lunar surface. We review lunar evolution models to identify candidate mantle lithologies, then assess orbital observations to evalutae the current distribution of these materials and implications for fundamental planetary processes.

    • Daniel P. Moriarty III
    • Nick Dygert
    • Noah E. Petro
    Perspective Open Access
  • A key feature of living cells is the cell cycle. In this Perspective, the authors explore attempts to recreate this process and what is still required for an integrated synthetic cell cycle.

    • Lorenzo Olivi
    • Mareike Berger
    • John van der Oost
    Perspective Open Access
  • Mosquito-borne diseases pose significant global health burdens. In this review, the authors explore Wolbachia and genome engineering approaches to mosquito-borne disease population control.

    • Guan-Hong Wang
    • Stephanie Gamez
    • Omar S. Akbari
    Review Article Open Access
  • Many different methods have been developed to forecast climate phenomena like the El Nino-Southern Oscillation (ENSO) which makes a fair comparison of their capabilities crucial. In this perspective, the authors discuss how choices in the evaluation method can lead to an overestimated perceived skill of ENSO forecasts.

    • James S. Risbey
    • Dougal T. Squire
    • Carly R. Tozer
    Perspective Open Access
  • The application space for optical fibers is growing, enabled by fibers built using special materials and processes. In this Review, the authors discuss the materials science behind producing crystalline core fibers for diverse applications and progress in the field.

    • Ursula J. Gibson
    • Lei Wei
    • John Ballato
    Review Article Open Access
  • Natural products are an important source of bioactive compounds and have versatile applications in different fields, but their discovery is challenging. Here, the authors review the recent developments in genome mining for discovery of natural products, focusing on compounds from unconventional microorganisms and microbiomes.

    • Kirstin Scherlach
    • Christian Hertweck
    Review Article Open Access
  • Antimicrobial resistance is a growing global problem and low dimensional materials have emerged as a potential solution. Here, the authors review the progress which has been made on low dimensional antimicrobials looking at the materials synthesis, modes of action and currently applications.

    • Z. L. Shaw
    • Sruthi Kuriakose
    • Sumeet Walia
    Review Article Open Access