Browse Articles

The high non-radiative energy loss is a bottleneck issue for efficient organic solar cells. Here, the authors regulate the charge transfer state disorder and rate of back charge transfer through a ternary system, achieving low non-radiative energy loss of 0.183 eV and device efficiency of 20.25%.

The industrial application of direct electrocatalytic epoxidation of olefins is limited by the low selectivity, low yield, and poor stability of the electrocatalysts. Here the authors report a universal electrochemical epoxidation approach via a kinetically confined surface radical pathway.

The authors revisit ultrafast fiber lasers with anomalous dispersion to propose a new laser design enhancing dissipative effects. Their approach yields high-energy few-picosecond pulses, blending soliton features for improved flexibility and scalability.

Drawing from historical tradition, “groove & tongue” sliding assembled devices were created in a one-pot microfluidic fabrication system, enabling the production of complex-shaped microparticles with high precision.

Understanding the antibody response to influenza neuraminidase (NA) can identify protective epitopes. Here, the authors isolate an antibody from an H5N6 infected patient, characterize the epitope on the N6 tetramer, and show that it’s protective in female mice.

Tetrapyrroles such as heme and chlorophyll, which are essential for various metabolic pathways, are synthesized from 5-aminolevulinic acid (5-ALA). Here, the authors identify functional 5-ALA synthase genes in bacteriophage sequences from aquatic environments, thus highlighting the importance of tetrapyrrole metabolism in phage biology.

Seawater direct electrolysis using renewable energy provides an appealing pathway to harness abundant oceanic hydrogen resources. Here, authors report a redox-mediated decoupled seawater direct electrolysis strategy to suppress the chlorine electro-oxidation side reaction.

Anlotinib hydrochloride is a multi-target tyrosine kinase receptor inhibitor, previously combined with anti-PD1 as therapeutic strategy for several cancer types. Here the authors report the results of a phase II trial of nivolumab (anti-PD1) plus anlotinib hydrochloride in patients with advanced gastric adenocarcinoma and esophageal squamous cell carcinoma.

The deep-water cycle in the mantle enhances chemical reactions between mantle minerals and the metallic core, contributing to seismic anomalies observed at the core-mantle boundary, according to high-pressure/temperature multi-anvil experiments.

The significance of biofluorescence across taxonomic groups is understudied. Here the authors document biofluorescence in South American tropical amphibians, suggesting that biofluorescence corresponds with wavelengths of light at twilight and may be used in communication.

Non-invasive approaches for risk stratification and screening remain crucial for colorectal cancer (CRC). Here, the authors develop a model for CRC risk stratification by integrating plasma proteomics data with polygenic risk score and QCancer-15 risk score, which could guide recommendations for earlier screening of high-risk populations.

The authors introduce the concepts of Robo-Matter and Robot-Matter duality, using magnetic spinner micro-robots. A wide range of functionalities and applications beyond the capability of both traditional inert and active materials is enabled.

Primary or acquired resistances to immune checkpoint inhibitors are often observed in patients with melanoma. Here the authors report the development of a method, immunotherapy resistance cell-cell interaction scanner (IRIS), for identifying cell-type-specific ligand-receptor interactions relevant to immunotherapy therapy response and resistance in melanoma.

The study of magnetic-related phenomena under high-pressure conditions currently presents significant challenges. The authors develop an in-situ magnetic imaging technique at megabar pressures, revealing the magnetic transition of magnetite.

Response to tebentafusp is variable in patients with metastatic uveal melanoma. Here, the authors use droplet digital PCR to detect ctDNA and show that ctDNA positivity was associated with shorter overall survival.

Thermal performance models support metabolic modeling in diverse contexts. Here, the authors compare 83 existing models with 2739 thermal performance datasets, finding that model performance doesn’t necessarily depend on the trait type, sampling resolution, or taxon being studied.

Low dose-radiation therapy (LDRT) can promote anti-tumor immune responses. Here the authors propose to combine the immunostimulatory properties of LDRT with the cell killing/shrinkage properties of high dose RT within the same tumor mass as a strategy to optimize RT-induced anti-tumor immune responses.