Microscopic image of parasites in lung tissue

Impact of pulmonary African trypanosomes on the immunology and function of the lung

Sleeping sickness is a disease caused by Trypanosoma parasites. Mabille et al. study how the parasites (colourized in the image) affect respiratory function and lung immune responses.

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Latest Research articles

  • The development of a nitrogen fixation process that relies on the renewable energy, such as visible light, is an important goal in sustainable chemistry. Here, authors establish an iridium and molybdenum-catalysed ammonia formation from dinitrogen driven by visible light under ambient reaction conditions.

    • Yuya Ashida
    • Yuto Onozuka
    • Yoshiaki Nishibayashi
    Article Open Access
  • Conventional wet chemistry method represents an inefficient way for bulk crystal synthesis. Here, the authors report a universal approach using electrical and mechanical field-assisted sintering technique to generate halide perovskites from solid precursors into large bulk crystal within minutes.

    • Luyao Zheng
    • Amin Nozariasbmarz
    • Kai Wang
    Article Open Access
  • The Schmidt reaction enables nitrogen insertion across an aldehyde or ketone substrate by frequently using azide reagents. Here, the authors show a Schmidt reaction of aryldiazonium salts as a replacement of azide reagents to access skeletally diverse cyclic lactams.

    • Fan-Tao Meng
    • Ya-Nan Wang
    • Bo Jiang
    Article Open Access

Subjects within Physical sciences

  • Climate change and earlier snowmelt could potentially extend the growing season for alpine grassland plants. Here, the authors combine field and chamber controlled experiments to show that extending the summer period did not result in prolonged root and leaf growth.

    • Patrick Möhl
    • Raphael S. von Büren
    • Erika Hiltbrunner
    Article Open Access
  • Glacial erosion processes over geological timescales are poorly understood. Here the authors apply an observationally constrained model to reconstruct the evolving thermodynamics and transient erosional signature of the Eurasian Ice Sheet over the last 100,000-year ice age to reveal how it profoundly sculpted but also protected the landscape visible today

    • H. Patton
    • A. Hubbard
    • K. Andreassen
    Article Open Access

Subjects within Earth and environmental sciences

  • Understanding the emergence, evolution, and transmission of antibiotic resistance genes (ARGs) is essential to combat antimicrobial resistance. Here, Munk et al. analyse ARGs in hundreds of sewage samples from 101 countries and describe regional patterns, diverse genetic environments of common ARGs, and ARG-specific transmission patterns.

    • Patrick Munk
    • Christian Brinch
    • Frank M. Aarestrup
    Article Open Access
  • Opportunistic bacterial pathogen species frequently colonise the human gut as a normal part of the ecosystem but strain-level colonisation and competition dynamics in healthy hosts is yet to be established. Authors seek to understand the relationship between colonisation potential and ecological factors modulating pathogen prevalence in disease in a longitudinal cohort.

    • Tommi Mäklin
    • Harry A. Thorpe
    • Jukka Corander
    Article Open Access
  • How the human visual system leverages the rich structure in object motion for perception remains unclear. Here, Bill et al. propose a theory of how the brain could infer motion relations in real time and offer a unifying explanation for various perceptual phenomena.

    • Johannes Bill
    • Samuel J. Gershman
    • Jan Drugowitsch
    Article Open Access
  • Bacteria are equipped with diverse immune strategies to fight bacteriophage infections, including restriction nucleases, abortive infection and CRISPR-Cas systems. Here, Arias et al. use mathematical models of immune responses in individual bacterial cells to highlight the importance of the timing and coordination of different antiviral systems, and present hypotheses that may inspire future research.

    • Clemente F. Arias
    • Francisco J. Acosta
    • Cristina Fernández-Arias
    Article Open Access

Subjects within Biological sciences

  • Accurate prediction of the onset of childhood allergy is important to clarify the difference between various respiratory diseases. Here the authors propose that the methylation status of three sites in nasal DNA predicts the onset of childhood allergy which may aid diagnosis and monitoring.

    • Merlijn van Breugel
    • Cancan Qi
    • Cheng-Jian Xu
    Article Open Access
  • Opportunistic bacterial pathogen species frequently colonise the human gut as a normal part of the ecosystem but strain-level colonisation and competition dynamics in healthy hosts is yet to be established. Authors seek to understand the relationship between colonisation potential and ecological factors modulating pathogen prevalence in disease in a longitudinal cohort.

    • Tommi Mäklin
    • Harry A. Thorpe
    • Jukka Corander
    Article Open Access
  • In situ generated lesion of red blood cells decreases the quality of stored blood and limits its shelf-life. Here, the authors demonstrate that intermittent scavenging of storage lesions using electrostatic interactions by nanofibrous sheets could enhance the quality and shelf-life of stored blood.

    • Subhashini Pandey
    • Manohar Mahato
    • Praveen Kumar Vemula
    Article Open Access
  • The SARS-CoV-2 Omicron variant is associated with less severe disease but less is known about variant-specific risk of long-term complaints. Monitoring 1.3 million individuals from Norway for post-acute COVID-19 complaints up to 126 days shows that the burden is similar for Omicron and Delta for most complaints except for musculoskeletal pain.

    • Karin Magnusson
    • Doris Tove Kristoffersen
    • Jonas Minet Kinge
    Article Open Access

Subjects within Health sciences

  • Misinformation online can be shared by major political figures and organizations. Here, the authors developed a method to measure exposure to information from these sources on Twitter, and show how exposure relates to the quality of the content people share and their political ideology.

    • Mohsen Mosleh
    • David G. Rand
    Article Open Access
  • The COVID-19 pandemic has stimulated an important changes in online information access. Here, the authors analyse everyday web search interactions across 25,150 US ZIP codes revealing significant differences in how digital informational resources are mobilized by different communities.

    • Jina Suh
    • Eric Horvitz
    • Tim Althoff
    Article Open Access
  • Systemic risk and bank bailout approaches have been the source of discussions on scientific, financial and governmental forums. An artificial intelligence technique is proposed to inform equitable bailout decisions that minimise taxpayers’ losses.

    • Daniele Petrone
    • Neofytos Rodosthenous
    • Vito Latora
    Article Open Access
  • In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.

    • Anderson F. Brito
    • Elizaveta Semenova
    • Nuno R. Faria
    Article Open Access

Subjects within Scientific community and society

  • The rapid expansion and globalization of the seaweed production industry, combined with rising seawater temperatures and coastal eutrophication, has led to an increase in infectious diseases and pest outbreaks. Here, we propose a novel Progressive Management Pathway for improving Seaweed Biosecurity.

    • Elizabeth J. Cottier-Cook
    • Jennefe P. Cabarubias
    • Melba G. Bondad-Reantaso
    Comment Open Access
  • Association genetic studies and genome-scale CRISPR screens have recently identified ARF3 and TMEM251/LYSET/GCAF as Golgi-resident factors essential to brain and skeletal development. Here we discuss how even though the consequences of mutations in these genes affect endosomal and lysosomal compartments, the problem originates in the Golgi complex and may involve either the identity of the carrier vesicles or that of cargo molecules.

    • Vincent El Ghouzzi
    • Gaelle Boncompain
    Comment Open Access
  • Since 2020 Nature Communications has been considering Registered Reports for publication in the areas of cognitive neuroscience, human behaviour and psychology, and epidemiology. We are excited to announce the publication of our first Registered Report. With this milestone, we also want to open the format to all other areas of research.

    Editorial Open Access
  • We recently published our first Registered Report entitled ‘Value-free random exploration is linked to impulsivity’. We believe the format offers many benefits to strengthen hypothesis-driven research and are keen to share our experience with our readers as we open up the format to all fields of research. We interviewed the authors of the manuscript (Magda Dubois and Tobias Hauser) and one of the reviewers (Trevor Robbins) about their experience of the review process. We are editorially committed to take their comments on board to further improve our guidance and to optimally support our future authors.

    Q&A Open Access
  • Nature Communications is now welcoming Registered Report submissions from all fields of research (read our editorial here), and we want to encourage submissions from the ecology and evolutionary biology fields. To introduce this format to researchers in those fields, we interviewed two founding members of the Society for Open, Reliable, and Transparent Ecology and Evolutionary Biology (SORTEE), a network of researchers aimed at improving research practices in ecology, evolutionary biology, and related fields: Shinichi Nakagawa (Professor of Evolutionary Ecology and Synthesis at the University of New South Wales, UNSW) and Rose O’Dea (Secretary of SORTEE, postdoctoral researcher and fellow at the Wissenschaftskolleg zu Berlin). Below, they share their thoughts on how the fields of ecology and evolutionary biology can advance in reproducibility and transparency.

    Q&A Open Access
  • While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating diverse ancestries in these models to improve equity and accelerate biological discovery.

    • Sulagna Ghosh
    • Ralda Nehme
    • Lindy E. Barrett
    Comment Open Access
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From brain to behaviour

On this page, we highlight some of the most exciting neuroscience papers that advance our understanding of the brain, covering neurodegeneration, neurological diseases, psychology, cognitive neuroscience, systems neuroscience, neurophysiology, neurotechnologies, computational neuroscience, and neurodevelopment.
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