Sammy Nyongesa, Philipp Weber et al. study cell shape and cell division in a family of bacteria, some of which divide in unusual ways and form caterpillar-like multicellular structures… in your mouth!
Recent development of analytical techniques – capable of characterizing physicochemical properties during electrochemical measurements – enables new pathways for improving the fundamental understanding of battery systems. This editorial highlights recent research efforts showcasing operando approaches published in Nature Communications.
For nearly a decade, Nature Portfolio journals have asked for information about sex and gender in research studies, and more recently, we have also encouraged authors to use the Sex and Gender Equity in Research (SAGER) guidelines in their work. We are now updating our guidance and practice so that authors are more clearly and actively encouraged to report on select items within the SAGER guidelines.
Graphene and related two-dimensional (2D) materials have been at the core of intense research and development for over fifteen years, however the market penetration of products based on this technology has lagged behind expectations. At Nature Communications we wish to support research providing insights into the path towards the industrialisation of 2D materials. We introduce a Collection that encapsulates the recent progress and outstanding challenges faced by research on atomically thin materials, and we focus, in particular, on the potential of 2D technologies for future impact at the commercial level.
Our Community Voices series aims to highlight the challenges faced by under-represented groups in scientific research and to provide a platform to share possible solutions, to work towards a more diverse and equitable research landscape.
Our editors highlight articles they see as particularly interesting or important in these new pages spanning all research areas.
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This Collection highlights recent publications in Nature Communications and Communications Materials on the discovery of natural materials and their potential applications as biomaterials. We also highlight how lessons learned from Nature can help develop advanced biomimetic materials, and explore their diverse applicationsOpen for submissions
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Latest Research articles
Sensitivity to noise is currently an obstacle to the use of quantum imaging techniques in real-world scenarios. Here, exploiting non-local cancellation of dispersion on time-frequency entangled photons, the authors show a 43dB improvement in resilience to noise for imaging protocols towards a quantum LiDAR.
Controlling the enantioselectivity of radical reactions is a persistent challenge in organic synthesis. Here, the authors report a method to form asymmetric pyridine derivatives via the combination of chiral palladium catalysis and electrochemistry.
Giant spin-to-charge conversion at an all-epitaxial single-crystal-oxide Rashba interface with a strongly correlated metal interlayer
The interface between perovskite-oxide SrTiO3 and other oxides realizes efficient spin-to-charge current conversion; however, the typically insulating oxides hinder the propagation of spin-currents. Here the authors achieve a record efficiency by replacing an oxide insulator with a strongly-correlated polar metal.
The authors present an approach to underwater imaging, which does not require tethering or batteries. The low-power camera uses power from harvested acoustic energy and communicates colour images wirelessly via acoustic backscatter.
Enantioselective synthesis of α-aminoboronates by NiH-catalysed asymmetric hydroamidation of alkenyl boronates
Enantioenriched α-aminoboronic acid, a structural unit in many bioactive molecules, is also a valuable synthon in organic synthesis. Here, the authors disclose a NiH-catalysed asymmetric hydroamidation process for their direct synthesis.
- Astronomy and planetary science
- Energy science and technology
- Materials science
- Mathematics and computing
- Nanoscience and technology
- Optics and photonics
Vertical exchange in the ocean is an important conduit connecting the surface to the deep and influences the distributions of gases, nutrients, pollutants, and other tracers. Here the authors using high-resolution observations and numerical simulations of the ocean fronts in the Northern Gulf of Mexico reveal that the interaction between the fronts and land-sea breeze creates slantwise pathways for water parcels and induces significant subduction of surface water and upwelling of bottom water.
Respiratory loss during late-growing season determines the net carbon dioxide sink in northern permafrost regions
The northern high latitude permafrost region has been an important contributor to the carbon sink since the 1980s. A new study finds that as tree cover increases, respiratory CO2 loss during late-growing season offsets photosynthetic CO2 uptake and leads to a slower rate of increasing annual net CO2 uptake.
A long-standing controversy surrounds low-angle nature of observed detachment faults within metamorphic core complexes. Here, the authors show that post-orogenic collapse of mountain belts can create a low-angle detachment, resolving the controversy.
Accurate estimates of carbon fluxes are important to our understanding of the carbon cycle. Here, via model-data integration, the authors disentangle anthropogenic and environmental carbon flux contributions of terrestrial woody vegetation, and find that environmental processes are weaker and more susceptible to interannual variations and extreme events in the 21st century than previously estimated.
A new study sheds light on earthquake physics, showing that lithological and rheological heterogeneities in the rocks composing the seismogenic layer strongly influence seismicity distributions and earthquake scaling laws.
- Climate sciences
- Environmental sciences
- Environmental social sciences
- Natural hazards
- Ocean sciences
- Planetary science
- Solid Earth sciences
- Space physics
Zymoseptoria tritici white-collar complex integrates light, temperature and plant cues to initiate dimorphism and pathogenesis
Transitioning from spores to hyphae is crucial for host invasion by the plant pathogenic fungus Zymoseptoria tritici. Here, the authors show that the spore-to-hypha transition is enhanced by wheat leaf surface compounds and is regulated by the white-collar complex, which integrates light with biotic and abiotic cues to allow host invasion through open stomata.
Diet affects the human gut microbiome, but studies linking crop genetics to seed traits that influence the human gut microbiome are lacking. Here, the authors develop an in vitro microbiome screening method and reveal the association between sorghum genes regulating condensed tannin biosynthesis and human gut microbiome.
The formation of branched microtubule networks in mitotic spindles depends on the augmin complex. Zupa, Würtz et al. elucidate the molecular architecture and conformational plasticity of the augmin complex using integrative structural biology, providing structural insights into microtubule branching.
During viral infections high levels of antibodies can form soluble immune complexes (sICs) with antigen and trigger Fcγ receptors (FcγR) leading to increased immunopathology. Here the authors measure FcγRs activation by sICs and consider how these may lead to excessive immunopathology during severe SARS-CoV-2 infection.
Modeling tissue-specific breakpoint proximity of structural variations from whole-genomes to identify cancer drivers
Identifying structural variants (SVs) under positive selection in cancer is challenging. Here, the authors develop CSVDriver, a method that computes SV breakpoint proximity and the contribution of elements such as topologically associating domains, and identifies loci that show signs of positive selection and contain known and putative drivers.
- Biological techniques
- Cell biology
- Chemical biology
- Computational biology and bioinformatics
- Developmental biology
- Drug discovery
- Molecular biology
- Plant sciences
- Stem cells
- Structural biology
- Systems biology
Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis
The functional role of airway basal cells has not been comprehensively studied in idiopathic pulmonary fibrosis (IPF). Here, the authors show that airway basal cells of IPF patients display a distinct phenotype, are profibrotic if transplanted to mice and that fibrosis can be ameliorated by Src iinhibitors.
USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer
IDO1-mediated tryptophan metabolism plays an important role in creating an immunosuppressive tumour microenvironment. Here, the authors show that deubiquitinase USP14 regulates immune suppression by inducing IDO1 stabilization and suggest USP14 as a potential therapeutic target to improve immunotherapy in colorectal cancer.
Estimating individual treatment effect on disability progression in multiple sclerosis using deep learning
There are limited predictive biomarkers for drug treatment responses in individuals with multiple sclerosis. Here using existing clinical trials data, the authors propose a deep-learning predictive enrichment strategy to identify which participants are most likely to respond to a treatment.
Frequency of cancer-related gene mutations can vary between populations. Here, the authors show differences in TP53 and other gene mutations between the U.S. and Chinese patients, and analyse differences in environmental risk factors to demonstrate that population-specific factors should be considered when discussing cancer risk.
Graphdiyne oxide nanosheets display selective anti-leukemia efficacy against DNMT3A-mutant AML cells
DNA methyltransferase 3A, a mutated gene associated with hematologic malignancies in age-related clonal haematopoiesis lacks targeted therapies. Here, the authors screen carbon nanomaterials and find graphdiyne oxide binds to mutant cells and disrupts cellular processes with a therapeutic effect in vitro and in vivo.
- Health care
- Health occupations
- Medical research
- Molecular medicine
- Risk factors
- Signs and symptoms
A new study assesses the feasibility of a fully renewable based power system by 2050 across India, finding this option to be cost competitive with the status quo and with zero GHG emissions.
This research quantifies the role of zero deforestation policies and potential leakages in Brazilian soybean production, the third major driver of deforestation globally. Here the authors provide the first estimates of net global avoided soy-driven deforestation from zero-deforestation import restrictions and find that such restrictions could help avoid ~40% of deforestation for soy cultivation in Brazil and ~2% of global deforestation.
The singlet fission mechanism is still not relatively well understood, except for polyacenes. Here, the authors demonstrate that in diketopyrrolopyrrole supramolecular assemblies, both singlet fission and intersystem crossing can simultaneously happen.
Wood used in construction stores carbon and reduces the emissions from steel and cement production. Transformation to timber cities while protecting forest and biodiversity is possible without significant increase in competition for land.
Selecting economic policies to achieve sustainable development is challenging due to the many sectors involved and the trade-offs implied. Artificial intelligence combined with economy-wide computer simulations can help.
Over the last two and a half years, Nature Communications has received thousands of submissions related to the COVID-19 pandemic and accepted hundreds for publication. To showcase the breadth and quality of this work, we are now launching a COVID-19 Collection, and here we reflect on our editorial processes during this period.
Most organelles move bidirectionally on microtubule tracks, yet how this opposing movement is regulated by kinesin and dynein remains unclear. Recent work found that ARL8, a known anterograde adaptor linking the lysosome to kinesin, also links lysosomes to the retrograde motor dynein, providing key insight into bidirectional organelle movement in cells.
Ways forward for Machine Learning to make useful global environmental datasets from legacy observations and measurements
Advances in geospatial and Machine Learning techniques for large datasets of georeferenced observations have made it possible to produce model-based global maps of ecological and environmental variables. However, the implementation of existing scientific methods (especially Machine Learning models) to produce accurate global maps is often complex. Tomislav Hengl (co-founder of OpenGeoHub foundation), Johan van den Hoogen (researcher at ETH Zürich), and Devin Routh (Science IT Consultant at the University of Zürich) shared with Nature Communications their perspectives for creators and users of these maps, focusing on the key challenges in producing global environmental geospatial datasets to achieve significant impacts.
The quest for high-energy electrochemical energy storage systems has driven researchers to look toward highly concentrated electrolytes. Here, the author discusses the recent progress and future perspectives of such electrolytes and their ability to improve the performances of lithium-based batteries.
Chirality of magnons is an intrinsic degree of freedom that characterizes the handedness of spin precession around its equilibrium direction. This commentary summarizes recent progress on spin pumping by ferromagnetic resonance in magnetic heterostructures. In particular, the commentary highlights one fundamental issue in spin pumping: the chirality dependence of the spin current.
CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups.
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Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination
A national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States
Extreme purifying selection against point mutations in the human genome
An anti-inflammatory activation sequence governs macrophage transcriptional dynamics during tissue injury in zebrafish