A portable bioluminescent platform for monitoring biological processes in live animals

Aleksey Yevtodiyenko et al. present a portable bioluminescent system that allows non-invasive measurement of enzymatic activities within the body of non-transgenic, live animals.


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Latest Research articles

Subjects within Physical sciences

  • Plant and soil C:N:P ratios are critical to ecosystem functioning, but it remains uncertain how plant diversity affects terrestrial C:N:P. In this meta-analysis of 169 studies, the authors find that plant mixtures can balance plant and soil C:N:P ratios according to background soil C:N:P.

    • Xinli Chen
    • Han Y. H. Chen
    Article Open Access
  • Here the authors show that 2-aminoethylphosphonate (2AEP) mineralisation is widespread in the global ocean, operating independently of exogenous inorganic phosphate concentration. They propose 2AEP may be a major route for the regeneration of phosphate required to support marine primary production.

    • Andrew R. J. Murphy
    • David J. Scanlan
    • Ian D. E. A. Lidbury
    Article Open Access
  • The global water demands of irrigated agriculture are estimated through country surveys or through hydrological models, but both approaches are taxing. Here, the authors show that they can simply be estimated as a function of irrigated areas.

    • Arnald Puy
    • Emanuele Borgonovo
    • Andrea Saltelli
    Article Open Access
  • How acute deoxygenation events affect tropical marine ecosystems remains poorly understood. This study integrates analyses of coral reef benthic communities with microbial community sequencing to show how a deoxygenation event rapidly altered a shallow tropical coral reef ecosystem in the Caribbean.

    • Maggie D. Johnson
    • Jarrod J. Scott
    • Andrew H. Altieri
    Article Open Access
  • A historical reconstruction of water use in Egypt shows the change in relative use of Nile water versus virtual water import, especially in the highly consumptive agriculture sector. A range of future projections of water demand are offered based on several plausible socioeconomic scenarios.

    • Catherine A. Nikiel
    • Elfatih A. B. Eltahir
    Article Open Access

Subjects within Earth and environmental sciences

  • COVID-19 is a critical public health threat, but molecular characterizations of patients’ immunity is still lacking. Here the authors collected blood from patients with various disease severity, and prefiltered to exclude selected comorbidity, to obtain genomic, transcriptomic, proteomic, metabolomic and lipidomic profiles to report a trans-omics landscape.

    • Peng Wu
    • Dongsheng Chen
    • Gang Chen
    Article Open Access
  • Endoplasmic reticulum (ER)-interorganelle membrane contact sites have emerged as key regulators of organelle dynamics. Here, the authors report that the ER-resident protein SNX19 mediates ER-endolysosome membrane contacts to maintain the perinuclear distribution of endolysosomes and restrict their motility.

    • Amra Saric
    • Spencer A. Freeman
    • Juan S. Bonifacino
    Article Open Access
  • Assembly of the mitoribosome requires assistance from numerous specialized factors. Here, structures of the human 39S late assembly intermediates identify several assembly factors which keep the 16S rRNA in immature conformations, and reveal deacylated tRNA in the ribosomal E-site, suggesting a role in 39S assembly.

    • Jingdong Cheng
    • Otto Berninghausen
    • Roland Beckmann
    Article Open Access
  • The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and arterioles creates an intravascular niche that precludes an effective action of neutrophils.

    • Valeria Manriquez
    • Pierre Nivoit
    • Guillaume Duménil
    Article Open Access

Subjects within Biological sciences

Subjects within Health sciences

  • This study combines ethnobotanical and epidemiological data to understand how social networks of seed exchange influence the genetic structure of the African cassava mosaic virus in Gabon. Results reveal contrasted patterns of viral diversity in patrilineal and matrilineal communities, consistent with cultural differences in modes of seed exchange.

    • Marc Delêtre
    • Jean-Michel Lett
    • Charles Spillane
    Article Open Access
  • National parochialism is the tendency to cooperate more with people of the same nation. In a 42-nations study, the authors show that national parochialism is a pervasive phenomenon, present to a similar degree across all the studied nations, and occurs both when decisions are private or public.

    • Angelo Romano
    • Matthias Sutter
    • Daniel Balliet
    Article Open Access
  • Understanding of complex contagions is crucial for explaining diffusion processes in networks. Guilbeault and Centola introduce topological mechanisms and measures to elucidate spreading dynamics and identify the most influential nodes in social, epidemic and economic networks.

    • Douglas Guilbeault
    • Damon Centola
    Article Open Access

Subjects within Scientific community and society

  • In the face of an on-going global pandemic and the growing urgency of climate change, the challenge of building an equitable and sustainable world has never been greater. Thus, now more than ever, we want to support and highlight research efforts made at attaining the UN sustainable development goals.

    Editorial Open Access
  • From smartphones to electric vehicles, Li-ion batteries have revolutionized our daily lives. Here, we discuss the most important aspects that have enabled lithium-ion batteries to thrive, and introduce some of our articles that contribute to the evolution of these devices.

    Editorial Open Access
  • Lesbian, gay, bisexual, transgender and queer (LGBTQ+) scientists are an invisible minority that still faces harassment and discrimination. Fostering safe, designated LGBTQ+ environments is a way for the community to connect with each other and raise awareness. In honor of Pride Month (June 2021), Dr. Keisling (postdoctoral fellow at the Lamont-Doherty Earth Observatory of Columbia University), Dr. Le Bras (scientist at the Woods Hole Oceanographic Institution) and Dr. Ludka (postdoctoral researcher at the Scripps Institution of Oceanography) share with Nature Communications their experiences bringing together the LGBTQ+ community at geoscience conferences, and offer advice for how other disciplines can do the same.

    Q&A Open Access
  • The longevity of a lithium-ion battery is limited by cathode degradation. Combining atom probe tomography and scanning transmission electron microscopy reveals that the degradation results from atomic-scale irreversible structural changes once lithium leaves the cathode during charging, thereby inhibiting lithium intercalation back into the cathode as the battery discharges. This information unveils possible routes for improving the lifetime of lithium-ion batteries.

    • Baptiste Gault
    • Jonathan D. Poplawsky
    Comment Open Access
  • While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major implications for anti-cancer drug development.

    • Craig M. Bielski
    • Barry S. Taylor
    Comment Open Access
  • The fast-growing interest for two-dimensional (2D) nanomaterials is undermined by their natural restacking tendency, which severely limits their practical application. Novel porous heterostructures that coordinate 2D nanosheets with monolayered mesoporous scaffolds offer an opportunity to greatly expand the library of advanced materials suitable for electrochemical energy storage technologies.

    • Jie Wang
    • Victor Malgras
    • Yusuke Yamauchi
    Comment Open Access
Optics and photonics

Optics and photonics

This page highlights recent engaging work in the areas of optics and photonics, ranging from optical physics, materials, imaging, and communications, to techniques, integration and applications, at all wavelengths of the electromagnetic spectrum.

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