DNA synthesis for true random number generation

Secure data encryption increasingly needs large volumes of true random numbers. Linda Meiser et al. use the stochastic nature of DNA synthesis to obtain millions of gigabytes of unbiased randomness.


Latest research

Subjects within Physical sciences

  • Clays in soil impact atmospheric CO2 by stabilizing soil organic matter, yet the dynamics of this process under future climate conditions are unknown. Here the authors present a way to observe clay-carbon dynamics within micro-aggregates using 4D imaging and a customized microfluidic chip.

    • Judy Q. Yang
    • Xinning Zhang
    • Howard A. Stone
    Article Open Access
  • The regulation of aircraft engine NOx emissions was introduced to improve local air quality and reduce NOx emissions at altitude. Here, the authors find that greater fuel efficiency of aircrafts, and therefore lower CO2 emissions, could be preferable to reducing NOx emissions in terms of the aviation industries future climate impacts.

    • Agnieszka Skowron
    • David S. Lee
    • Bethan Owen
    Article Open Access
  • Melting of the Greenland Ice Sheet—a threat for sea level rise—is accelerated by ice algal blooms. Here the authors find a link between mineral phosphorus and glacier algae, indicating that dust-derived nutrients aid bloom development, thereby impacting ice sheet melting.

    • Jenine McCutcheon
    • Stefanie Lutz
    • Liane G. Benning
    Article Open Access
  • Forest structure depends both on extrinsic factors such as climate and on intrinsic properties such as community composition and diversity. Here, the authors use a dataset of stand structural complexity based on LiDAR measurements to build a global map of structural complexity for primary forests, and find that precipitation variables best explain global patterns of forest structural complexity.

    • Martin Ehbrecht
    • Dominik Seidel
    • Christian Ammer
    Article Open Access

Subjects within Earth and environmental sciences

Subjects within Biological sciences

Subjects within Health sciences

  • Neural recording technologies increasingly enable simultaneous measurement of neural activity from multiple brain areas. To gain insight into distributed neural computations, a commensurate advance in experimental and analytical methods is necessary. We discuss two opportunities towards this end: the manipulation and modeling of neural population dynamics.

    • Krishna V. Shenoy
    • Jonathan C. Kao
    Comment Open Access
  • Writing in Nature communications, Zhu and collaborators reported the development of a genetically encoded sensor for the detection of formaldehyde in cells and tissues. This tool has great potential to transform formaldehyde research; illuminating a cellular metabolite that has remained elusive in live structures.

    • Carla Umansky
    • Agustín E. Morellato
    • Lucas B. Pontel
    Comment Open Access
  • Many newly-discovered microbial phyla have been studied solely by cultivation-independent techniques such as metagenomics. Much of their biology thus remains elusive, because the organisms have not yet been isolated and grown in the lab. Katayama et al. lift the curtain on some intriguing biology by cultivating and studying bacteria from the elusive OP9 phylum (Atribacterota).

    • Muriel C. F. van Teeseling
    • Christian Jogler
    Comment Open Access
  • The publication of a paper on mentorship, now retracted, led us to reflect on our editorial processes and strengthened our determination in supporting diversity, equity and inclusion in research.

    Editorial Open Access
  • Dr Nicolas Mano is a Senior Researcher at Centre de Recherche Paul Pascal, France. His research interests include (bio)electrochemistry, biosensors, biofuel cells, enzymes engineering, and the use of carbonaceous materials for electrodes. His aim is to develop approaches where biochemical fuels can be converted into electricity and applied into bioelectrochemical applications. In this conversation, he is discussing the advancements in the field of biofuel cells in the past ten years and look ahead at future developments.

    Q&A Open Access
AI and machine learning

AI and machine learning

A periscope into the broad-ranging applications of machine learning and how it is enabling new research and tools, reducing inequality and increasing quality of life – with a focus on the general pursuit of laying the foundations of Artificial Intelligence.

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