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Compensating transport trends in the Drake Passage frontal regions yield no acceleration in net transport

Manuel Gutierrez-Villanueva et al. find increased eddy activity in the Antarctic Circumpolar Current, which could promote upwelling of deep warm waters and affect ice melt and sea level rise.


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Latest Research articles

Subjects within Physical sciences

  • A characteristic of costal-pelagic fishes is their large population size fluctuations, yet the drivers remain elusive. Here, the authors analyze a 45-year timeseries of nitrogen stable isotopes measured in larvae of Northern Anchovy and find that high energy transfer efficiency from the base of the food web up to young larvae confers high survival and recruitment to the adult population.

    • Rasmus Swalethorp
    • Michael R. Landry
    • Andrew R. Thompson
    ArticleOpen Access
  • Forecasting ecology can support proactive decision-making in the face of uncertain environmental conditions. Using case studies on whale entanglement and sea turtle bycatch, this study showcases the capacity for existing management tools to transition to a forecast configuration and provide skilful forecasts up to 12 months in advance.

    • Stephanie Brodie
    • Mercedes Pozo Buil
    • Michael G. Jacox
    ArticleOpen Access
  • Research on electrochemical nitrate reduction to ammonia in acidic conditions has been less extensive than that conducted in alkaline conditions. Here, the authors report a hybrid of iron phthalocyanine and TiO2 catalyst with improved efficiency toward acidic nitrate reduction and its application in Zn-nitrate batteries and high-voltage pollutes-based fuel cell.

    • Rong Zhang
    • Chuan Li
    • Chunyi Zhi
    ArticleOpen Access

Subjects within Earth and environmental sciences

  • Pathogenic variants of DDX3X are associated with neurodevelopmental disorders (NDD) and cancer. Here, the authors perform saturation genome editing of DDX3X to test the functional impact of 12,776 variants, develop a machine learning classifier to identify variants relevant for NDD, and show that DDX3X predominantly acts as a tumour suppressor in cancer.

    • Elizabeth J. Radford
    • Hong-Kee Tan
    • Matthew E. Hurles
    ArticleOpen Access
  • The ability of T cells to migrate is a central component of their functionality and is known to require WNK1 kinase that is linked to the influx of ions into the cell. Here the authors show that T cell migration requires WNK1 mediated ion and water influx to swell the membrane of the leading edge and support actin polymerisation and forward motility.

    • Leonard L. de Boer
    • Lesley Vanes
    • Victor L. J. Tybulewicz
    ArticleOpen Access
  • The Omicron BA.2.86 subvariant differs from previous variants by over 30 spike mutations. Here, the authors report that BA.2.86 likely evolved in Southern Africa and that its immune escape is not larger than recently circulating SARS-CoV-2 strains. Neither its replication nor its pathogenicity are enhanced in vitro.

    • Khadija Khan
    • Gila Lustig
    • Alex Sigal
    ArticleOpen Access

Subjects within Biological sciences

Subjects within Health sciences

Subjects within Scientific community and society

  • Endometriosis is an incurable, under-diagnosed, systemic inflammatory disease affecting millions world-wide. Common symptoms include life-impacting pain, gastrointestinal/urinary symptoms, excessive fatigue, and infertility. Global public health policies are urgently needed to promote awareness, implement multidisciplinary care, and fund research for aetiology, biomarker discovery, and effective therapies for symptoms associated with endometriosis.

    • Linda C. Giudice
    • Andrew W. Horne
    • Stacey A. Missmer
    CommentOpen Access
  • Despite significant progress in CO2 conversion field, there remains a significant gap between fundamental research and the industrial demands. This Comment discusses key performance parameters for industrial applications and outlines current limitations in the field.

    • Doris Segets
    • Corina Andronescu
    • Ulf-Peter Apfel
    CommentOpen Access
  • Optimisation tasks in the inverse design of metamaterials with machine learning were limited due to the representations of generative models. Here the author comments a recent publication in Nature Communications which generates a latent space representation that unlocks non-linear optimisations.

    • Angkur Jyoti Dipanka Shaikeea
    CommentOpen Access
  • The exploration of our solar system is being radically changed since the beginning of operations of the James Webb Space Telescope (JWST) in mid 2022. JWST’s extraordinary sensitivity and instrumentation allow for sensitive searches for the building blocks of life and to test for habitability, also enabling new discoveries on small bodies to giant planets across our solar system and beyond.

    • G. L. Villanueva
    • S. N. Milam
    CommentOpen Access
  • Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.

    • Young Min Park
    • De-Chen Lin
    CommentOpen Access

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