Based on the design of natural, porous organic nanotubes, Shuangqiao Han et al. fabricate 15 nm thin membranes that can be used for water purification, specifically to filter out boron and phosporus.
Starting in 2016, we have offered authors the option to publish the comments received from the reviewers and their responses alongside the paper. As we believe that transparency strengthens the quality of peer review, we are now moving to publish the exchanges between authors and reviewers for all research articles submitted from November 2022 onward and accepted for publication. Referees will still have the option to remain completely anonymous, to sign their reports, and/or to choose to be acknowledged by name as part of our reviewer recognition scheme.
Earthquakes are a natural hazard affecting millions of people globally every year. Researchers are working on understanding the mechanisms of earthquakes and how we can predict them from various angles, such as experimental work, theoretical modeling, and machine learning. We invited Marie Violay (EPFL Lausanne), Annemarie Baltay (USGS), Bertrand Rouet-Leduc (Kyoto University) and David Kammer (ETH Zürich) to discuss how such a multi-disciplinary approach can advance our understanding of Earthquakes.
Rigorous, robust replication and generalization studies present a significant investment into the quality of the research record, the foundation on which new research is built. Communications Psychology and the Human Behaviour Team at Nature Communications are inviting submissions of replication studies in psychology and the human behavioural sciences.
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Our editors highlight articles they see as particularly interesting or important in these new pages spanning all research areas.
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Latest Research articles
Organoboron and organosilicon compounds have potential applications in various fields including materials science and medicinal chemistry. Here the authors report a protocol that enables the dearomative carbo-sila-boration of quinolines.
Conformation-dependent dynamic organic phosphorescence through thermal energy driven molecular rotations
Organic room-temperature phosphorescent (RTP) materials exhibiting stimuli responsive reversible changes in optical properties show great potential in diverse optoelectronic fields but a lack of mechanistic understanding limits their development. Here, the authors prepare a series of RTP polymers by incorporating phosphorescent rotors into polymer backbones and demonstrate colortunable persistent luminescence upon excitation at different wavelengths
The large radius of potassium ions inevitably destabilizes the crystal structure of the cathode material in potassium-ion batteries, leading to capacity degradation. Here, authors demonstrate that phase-engineered amorphous vanadium oxide alleviates large volume variation and improves electrochemical behaviour.
Zinc metal anodes suffer from electrolyte corrosion and dendrite growth issues during electrochemical cycling. Here, the authors propose a gradient design to imprint the zinc anode, which both prohibits side reactions and alleviates zinc deposition behaviour.
Ruthenium-based materials show promising performance for ammonia decomposition, yet the underlying mechanism remains to be further explored. Here the authors investigate atomically dispersed Ru atoms on polar (111) on MgO facets to show synergistic metal sites in close proximity are required for the stepwise dehydrogenation of ammonia to N2/H2.
- Astronomy and planetary science
- Energy science and technology
- Materials science
- Mathematics and computing
- Nanoscience and technology
- Optics and photonics
Evidence for a rosiaite-structured high-pressure silica phase and its relation to lamellar amorphization in quartz
Rapid compression experiments on quartz provide evidence for a metastable high-pressure phase with rosiaite structure. The phase forms as lamellae and breaks down to glass during decompression. These discoveries may solve the enigma of lamellar amorphization of quartz during impact events.
Origins of Barents-Kara sea-ice interannual variability modulated by the Atlantic pathway of El Niño–Southern Oscillation
This paper finds that the winter sea-ice over the Barents-Kara Seas has exhibited strengthened interannual variations in recent decades likely due to increased amplitudes of the El Niño-Southern Oscillation in a warming climate.
Zooplankton are a critical link to higher trophic levels and play an important role in global biogeochemical cycles. This Review examines key responses of zooplankton to ocean warming, highlights key knowledge and geographic gaps that need to be addressed, and discusses how better use of observations and long-term zooplankton monitoring programmes can help fill these gaps.
Gelatinous bloom-forming zooplankton—salps—alter microbial communities and quintuple the flux of sinking particles from the surface to the deep, strongly enhancing the ability of the ocean to sequester CO2.
Here, the authors show that pre-existing equatorial waves are useful precursors to tropical cyclone occurrence and intensification up to two weeks ahead.
- Climate sciences
- Environmental sciences
- Environmental social sciences
- Natural hazards
- Ocean sciences
- Planetary science
- Solid Earth sciences
- Space physics
Barrier-to-autointegration factor 1 (BAF) is a DNA binding protein involved in numerous pathways including transcriptional regulation, DNA damage response and nuclear assembly. Here, Broussard and colleagues characterise its role in gammaherpesvirus reactivation.
DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage
The extensive information capacity of DNA makes it an attractive alternative to traditional data storage. DNA-Aeon is a DNA data storage solution that can correct all error types commonly observed in DNA storage, while encoding data into sequences that meet user-defined constraints such as GC content, homopolymer length, and no undesired motifs.
There are limitations with current protein sensing methods. Here the authors report DigitISA, a digital immunosensor assay based on microchip electrophoretic separation and single-molecule detection that enables quantitation of protein biomarkers in a single, solution-phase step.
The NLRP3 inflammasome plays a pivotal role in clearing viral respiratory infection, but the molecular mechanism is not fully known. Here authors show that acetate, produced by gut bacteria, may enhance NLRP3-mediated type I interferon production following influenza infection in mice.
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition
Inter-organellar contacts are hubs for several critical cellular processes, such as lipid synthesis. Here Ganji et al. show that the p97-UBXD8 complex modulates contacts by regulating membrane lipid composition and saturation.
- Biological techniques
- Cell biology
- Chemical biology
- Computational biology and bioinformatics
- Developmental biology
- Drug discovery
- Molecular biology
- Plant sciences
- Stem cells
- Structural biology
- Systems biology
Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
Idiopathic pulmonary fibrosis is a disease caused by persistent micro-injuries to the lung ultimately resulting in death. Here, the authors describe the use of a small molecule OGG1 inhibitor, TH5487, as a potent and potentially clinically relevant treatment for IPF.
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Marchioretti and colleagues show that in the skeletal muscle of SBMA mice and patients there is an early, but reversible alteration of expression of genes involved in muscle contraction and of mitochondrial respiration, followed by accumulation of calcium inside the mitochondria, which is concomitant with the onset of motor dysfunction, and late alteration of muscle structure.
Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection
Developing multi-cancer early detection (MCED) tests based on cfDNA or protein markers holds great promise for effective cancer screening. Here, the authors show a sensitive, non-invasive pan-cancer detection method that concurrently detects the oncofetal chondroitin sulfate (ofCS) glycans and its protein backbone in plasma.
In biliary tract cancer HER2 alterations correlate with poor prognosis. Here, the authors present the results of a phase II clinical trial reporting the efficacy and safety of the tyrosine kinase inhibitor neratinib in patients with HER2-mutation positive advanced biliary tract cancers.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Here, Prakasam and colleagues show that polyQ-expanded androgen receptor toxicity can be attenuated using artificial miRNAs targeting Lsd1 and Prmt6, two AR-co-activators overexpressed in an androgen-dependent manner specifically in skeletal muscle, thus ameliorating spinal-bulbar muscular atrophy phenotypes in flies and mice.
- Health care
- Health occupations
- Medical research
- Molecular medicine
- Risk factors
- Signs and symptoms
A scoping review of the impacts of COVID-19 physical distancing measures on vulnerable population groups
Physical distancing measures introduced to control the spread of COVID-19 had socio-economic trade-offs that may have particularly impacted vulnerable population groups. Here, the authors perform a scoping review and summarise the impacts on different vulnerable groups described in 265 studies.
Exposure to the Russian Internet Research Agency foreign influence campaign on Twitter in the 2016 US election and its relationship to attitudes and voting behavior
Here, using longitudinal survey and Twitter data, the authors examine the relationship between exposure to Russian Internet Research Agency activities on Twitter and voting behavior and attitudes in the 2016 US election.
The authors show that accurate information about descriptive norms can increase intentions to accept a vaccine for COVID-19. They show that these effects are largely consistent in the 23 included countries and are concentrated among people who were otherwise uncertain about accepting a vaccine.
Liu et al. used the NASA GRACE/FO missions to show that since 2019, groundwater depletion in California’s Central Valley has accelerated by 31% compared to recent droughts, and has increased by a nearly a factor of 5 compared to the 60-year average.
Using performance art to promote intergroup prosociality by cultivating the belief that empathy is unlimited
People tend to feel less empathy toward people who do not belong to their social group (outgroup members). Here, the authors show that leading people to believe that empathy is unlimited increases empathy, support for prosocial actions, and empathic behaviors toward outgroup members.
Every area of science can contribute to the changes that are required for a sustainable future through the application of its fundamental discoveries. While some fields have clear paths to application, Nature Communications believes that there is great potential for utility and application to be found in, and across, all of the different disciplines that we publish.
Prostate cancer is a highly heterogeneous disease. Progression on androgen deprivation therapy (ADT) to castration-resistant (CRPC), or neuroendocrine prostate cancer (NEPC), is associated with poor patient survival. This comment highlights recent evidence on the epigenetic mechanisms underlying the emergence of lineage plasticity and neuroendocrine differentiation in treatment-resistant prostate tumors.
Two new studies exploring PROTAC-mediated degradation of SMARCA2 for cancer therapy solve an apparently intractable selectivity challenge with SMARCA4 by utilising the requirement for a productive ternary complex between the protein, PROTAC and ligase complex.
Chalcogenide aerogels are receiving widespread attention due to their unique properties. Here we comment on a recent work about amorphous Na–Mn–Sn–S chalcogels featuring local structural control, and provide an outlook for the development of chalcogels and the metal-organic sulfide framework.
The development of photocatalysts is greatly hindered by false positives or non-reproducible data. Here, The authors describe the current known causes of non-reproducible results in the literature and present solutions to mitigate these false positive results.
Creative arts and digitial interventions as potential tools in prevention and recovery from the mental health consequences of adverse childhood experiences
Adverse childhood experiences (ACEs) can harm mental health across the lifespan and reduce life expectancy. We provide a commentary of evidence on the health impacts, and how creative arts and digital interventions may support prevention and recovery.
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