The rapid evolution of durophagy in lungfish

Xindong Cui et al. describe exceptionally preserved fossils of lungfish (air-breathing fish) from the Early Devonian that show early adaptations to durophagy, or the consumption of hard-shelled prey.


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Latest Research articles

Subjects within Physical sciences

  • Mineral-organic associations play a key role in soil carbon preservation. Here, Georgiou et al. produce global estimates of mineral-associated soil carbon, providing insight into the world’s soils and their capacity to store carbon

    • Katerina Georgiou
    • Robert B. Jackson
    • Margaret S. Torn
    Article Open Access
  • The authors present novel observations providing insights into the formation of extraordinary gold-rich veins. We discovered metal nanoparticles associated with amorphous silica and carbon indicating their essential contribution to efficient gold deposition.

    • Laura Petrella
    • Nicolas Thébaud
    • Sarah Gain
    Article Open Access
  • Albedo changes caused by projected future urban land expansion will contribute to global warming without proper mitigation. This warming effect will be larger under higher emission scenarios than under lower emission scenarios.

    • Zutao Ouyang
    • Pietro Sciusco
    • Jiquan Chen
    Article Open Access
  • The effects of fertiliser from intensive agriculture are well recognised, but not so well for fine-sediment. Here we show how widespread ingress of agriculturally derived fine-sediment since the 1940s markedly amplifies methane emissions from streams.

    • Yizhu Zhu
    • J. Iwan Jones
    • Mark Trimmer
    Article Open Access

Subjects within Earth and environmental sciences

  • The DEAD box protein DDX1 is known to form large aggregates in the cytoplasm of early mouse embryos. Here the authors identify DDX1-containing vesicles and show that loss of Ddx1 affects their integrity, compromising mitochondria function and causing embryonic lethality.

    • Yixiong Wang
    • Lubna Yasmin
    • Roseline Godbout
    Article Open Access
  • The authors provide a litmus test for the recognition mechanism of transiently binding proteins based on nuclear magnetic resonance and find a conformational selection binding mechanism through concentration-dependent kinetics of ubiquitin and SH3.

    • Kalyan S. Chakrabarti
    • Simon Olsson
    • Christian Griesinger
    Article Open Access
  • The role of IL-9 in the tumor microenvironment and its effects on macrophages remains unclear. Here, the authors show that IL-9 promotes the expansion of pulmonary macrophages and that targeting the IL-9R/arginase 1 axis restricts tumor growth, thus identifying this cytokine pathway as a potential therapeutic target.

    • Yongyao Fu
    • Abigail Pajulas
    • Mark H. Kaplan
    Article Open Access
  • Folded proteins are composed of secondary structures, α-helices and β-sheets, that are generally assumed to be stable. Here, the authors combine computational prediction with experimental validation to show that many sequence-diverse NusG protein domains switch completely from α-helix to β-sheet folds.

    • Lauren L. Porter
    • Allen K. Kim
    • Marie-Paule Strub
    Article Open Access

Subjects within Biological sciences

  • Cholesterol efflux is mediated by specific transporters in T cells. Here the authors show that when the ABCA1/ABCG1 cholesterol transporters are absent, peripheral T cell numbers are reduced but activation increased with a premature aging phenotype of T cell senescence and apoptosis in middle aged Ldlr−/− mice.

    • Venetia Bazioti
    • Anouk M. La Rose
    • Marit Westerterp
    Article Open Access
  • Nanomaterials have a range of potential applications, however, toxicity remains a concern, limiting application and requiring extensive testing. Here, the authors report on a predictive framework made using a range of tests linking materials properties with toxicity, allowing the prediction of toxicity from physiochemical and biological properties.

    • Vittorio Fortino
    • Pia Anneli Sofia Kinaret
    • Dario Greco
    Article Open Access
  • COVID-19 vaccines may reduce the susceptibility of an individual to infection and/or the infectiousness of breakthrough infections. Here, the authors use data from Denmark and estimate that vaccine effectiveness was 61% for susceptibility and 31% for infectiousness during a period of Delta variant dominance.

    • Frederik Plesner Lyngse
    • Kåre Mølbak
    • Carsten Thure Kirkeby
    Article Open Access

Subjects within Health sciences

Subjects within Scientific community and society

  • Flooding is a pervasive natural hazard, with new research demonstrating that more than one in five people around the world live in areas directly exposed to 1-in-100 year flood risk. Exposure to such flood risk is particularly concentrated amongst lower income households worldwide.

    • Thomas K. J. McDermott
    Comment Open Access
  • Our peer review programme was launched in 2020 to support Early Career Researchers in building confidence to participate in peer review. The initiative has proved very successful and popular with both ECRs and editors and we are pleased to invite applicants to apply to our 2022 programme.

    Editorial Open Access
  • Habitability of exoplanet’s deepest oceans could be limited by the presence of high-pressure ices at their base. New work demonstrates that efficient chemical transport within deep planetary ice mantles is possible through significant salt incorporation within the high-pressure ice.

    • Baptiste Journaux
    Comment Open Access
  • Diagonal integration of multimodal single-cell data emerges as a trending topic. However, empowering diagonal methods for novel biological discoveries requires bridging huge gaps. Here, we comment on potential risks and future directions of diagonal integration for multimodal single-cell data.

    • Yang Xu
    • Rachel Patton McCord
    Comment Open Access
  • A Global Forum on Synthetic Biology is needed to engage policymakers with practitioners across borders at the highest level. The international community needs a global confidence-building measure focused on discussing policy futures for the age of engineering biology.

    • Thomas A. Dixon
    • Paul S. Freemont
    • Isak S. Pretorius
    Comment Open Access
  • Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.

    • Archibald Enninful
    • Alev Baysoy
    • Rong Fan
    Comment Open Access

Translational and clinical research

This page highlights the most compelling studies recently published in Nature Communications with a significant translational potential and immediate impact in the medical field. In particular, we primarily cover studies concerning metabolism, cardiovascular research, organ and tissue biology, and ageing.


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