Iniguez-Rabago et al.

Exploring multistability in prismatic metamaterials through local actuation

Latest Research

Physical sciences

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  • Article
    | Open Access

    Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable tool and their dissociation upon exposure to light.

    • Dirk Ollech
    • , Tim Pflästerer
    • , Adam Shellard
    • , Chiara Zambarda
    • , Joachim Pius Spatz
    • , Philippe Marcq
    • , Roberto Mayor
    • , Richard Wombacher
    •  & Elisabetta Ada Cavalcanti-Adam
  • Article
    | Open Access

    The study of covalent organic frameworks (COFs) in electrocatalytic CO2 reduction reaction (CO2RR) has drawn much attention. Here the authors show a series of tetrathiafulvalene based COFs designed and exfoliated into nanosheets which exhibit high electrocatalytic CO2RR performance.

    • Hong-Jing Zhu
    • , Meng Lu
    • , Yi-Rong Wang
    • , Su-Juan Yao
    • , Mi Zhang
    • , Yu-He Kan
    • , Jiang Liu
    • , Yifa Chen
    • , Shun-Li Li
    •  & Ya-Qian Lan
  • Article
    | Open Access

    The role of of voltage-gated sodium channels (Nav) in pacemaking and conduction of the human sinoatrial node is unclear. Here, the authors investigate existence and function of neuronal and cardiac Nav in human sinoatrial nodes, and demonstrate their alterations in explanted human diseased hearts.

    • Ning Li
    • , Anuradha Kalyanasundaram
    • , Brian J. Hansen
    • , Esthela J. Artiga
    • , Roshan Sharma
    • , Suhaib H. Abudulwahed
    • , Katelynn M. Helfrich
    • , Galina Rozenberg
    • , Pei-Jung Wu
    • , Stanislav Zakharkin
    • , Sandor Gyorke
    • , Paul ML. Janssen
    • , Bryan A. Whitson
    • , Nahush A. Mokadam
    • , Brandon J. Biesiadecki
    • , Federica Accornero
    • , John D. Hummel
    • , Peter J. Mohler
    • , Halina Dobrzynski
    • , Jichao Zhao
    •  & Vadim V. Fedorov

Earth and environmental sciences

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  • Article
    | Open Access

    Egyptian rousette bats (ERBs) are natural reservoirs for Marburg virus (MARV), but these bats have not been linked to the MARV Angola strain that caused the largest and deadliest outbreak on record. Here, Amman et al., in a multi-institutional surveillance effort, identify and isolate Angola-like MARV in ERBs in West Africa.

    • Brian R. Amman
    • , Brian H. Bird
    • , Ibrahim A. Bakarr
    • , James Bangura
    • , Amy J. Schuh
    • , Jonathan Johnny
    • , Tara K. Sealy
    • , Immah Conteh
    • , Alusine H. Koroma
    • , Ibrahim Foday
    • , Emmanuel Amara
    • , Abdulai A. Bangura
    • , Aiah A. Gbakima
    • , Alexandre Tremeau-Bravard
    • , Manjunatha Belaganahalli
    • , Jasjeet Dhanota
    • , Andrew Chow
    • , Victoria Ontiveros
    • , Alexandra Gibson
    • , Joseph Turay
    • , Ketan Patel
    • , James Graziano
    • , Camilla Bangura
    • , Emmanuel S. Kamanda
    • , Augustus Osborne
    • , Emmanuel Saidu
    • , Jonathan Musa
    • , Doris Bangura
    • , Samuel Maxwell Tom Williams
    • , Richard Wadsworth
    • , Mohamed Turay
    • , Lavalie Edwin
    • , Vanessa Mereweather-Thompson
    • , Dickson Kargbo
    • , Fatmata V. Bairoh
    • , Marilyn Kanu
    • , Willie Robert
    • , Victor Lungai
    • , Raoul Emeric Guetiya Wadoum
    • , Moinya Coomber
    • , Osman Kanu
    • , Amara Jambai
    • , Sorie M. Kamara
    • , Celine H. Taboy
    • , Tushar Singh
    • , Jonna A. K. Mazet
    • , Stuart T. Nichol
    • , Tracey Goldstein
    • , Jonathan S. Towner
    •  & Aiah Lebbie
  • Article
    | Open Access

    Sulfur is one of the key volatiles in Earth’s chemical cycles; however, sulfur speciation, isotopic composition, and flux during the subduction cycle remain unclear. Here, the authors provide direct constraints on subduction zone sulfur recycling from high-pressure rocks and explore implications for arc magmatism.

    • Ji-Lei Li
    • , Esther M. Schwarzenbach
    • , Timm John
    • , Jay J. Ague
    • , Fang Huang
    • , Jun Gao
    • , Reiner Klemd
    • , Martin J. Whitehouse
    •  & Xin-Shui Wang
  • Article
    | Open Access

    Ecologists continue to debate whether local species assemblages result from habitat filtering or from turnover among the regional species pool. Here the authors develop a “dispersion field” method to mapping species range overlaps, showing that regional turnover processes are key to local assembly.

    • Michael K. Borregaard
    • , Gary R. Graves
    •  & Carsten Rahbek

Biological sciences

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  • Article
    | Open Access

    Gut microbiota and their metabolites regulate homeostasis of the intestine, but their effects on intestine development are unclear. Here the authors use RNAseq and germ free mice to show that intestinal microbiota promote the expression of Erdr1, which increases Lgr5+ intestinal stem cell number and activity.

    • Hirohito Abo
    • , Benoit Chassaing
    • , Akihito Harusato
    • , Miguel Quiros
    • , Jennifer C. Brazil
    • , Vu L. Ngo
    • , Emilie Viennois
    • , Didier Merlin
    • , Andrew T. Gewirtz
    • , Asma Nusrat
    •  & Timothy L. Denning
  • Article
    | Open Access

    Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable tool and their dissociation upon exposure to light.

    • Dirk Ollech
    • , Tim Pflästerer
    • , Adam Shellard
    • , Chiara Zambarda
    • , Joachim Pius Spatz
    • , Philippe Marcq
    • , Roberto Mayor
    • , Richard Wombacher
    •  & Elisabetta Ada Cavalcanti-Adam
  • Article
    | Open Access

    The role of of voltage-gated sodium channels (Nav) in pacemaking and conduction of the human sinoatrial node is unclear. Here, the authors investigate existence and function of neuronal and cardiac Nav in human sinoatrial nodes, and demonstrate their alterations in explanted human diseased hearts.

    • Ning Li
    • , Anuradha Kalyanasundaram
    • , Brian J. Hansen
    • , Esthela J. Artiga
    • , Roshan Sharma
    • , Suhaib H. Abudulwahed
    • , Katelynn M. Helfrich
    • , Galina Rozenberg
    • , Pei-Jung Wu
    • , Stanislav Zakharkin
    • , Sandor Gyorke
    • , Paul ML. Janssen
    • , Bryan A. Whitson
    • , Nahush A. Mokadam
    • , Brandon J. Biesiadecki
    • , Federica Accornero
    • , John D. Hummel
    • , Peter J. Mohler
    • , Halina Dobrzynski
    • , Jichao Zhao
    •  & Vadim V. Fedorov

Health sciences

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  • Article
    | Open Access

    The pathways that underlie the effects of exercise on metabolism remain incompletely described. Here, the authors perform a meta-analysis of transcriptomic data from 66 published datasets of human skeletal muscle. They identify pathways selectively activated by inactivity, aerobic or resistance exercise, and characterize NR4A3 as one of the genes responsive to inactivity.

    • Nicolas J. Pillon
    • , Brendan M. Gabriel
    • , Lucile Dollet
    • , Jonathon A. B. Smith
    • , Laura Sardón Puig
    • , Javier Botella
    • , David J. Bishop
    • , Anna Krook
    •  & Juleen R. Zierath
  • Article
    | Open Access

    The role of of voltage-gated sodium channels (Nav) in pacemaking and conduction of the human sinoatrial node is unclear. Here, the authors investigate existence and function of neuronal and cardiac Nav in human sinoatrial nodes, and demonstrate their alterations in explanted human diseased hearts.

    • Ning Li
    • , Anuradha Kalyanasundaram
    • , Brian J. Hansen
    • , Esthela J. Artiga
    • , Roshan Sharma
    • , Suhaib H. Abudulwahed
    • , Katelynn M. Helfrich
    • , Galina Rozenberg
    • , Pei-Jung Wu
    • , Stanislav Zakharkin
    • , Sandor Gyorke
    • , Paul ML. Janssen
    • , Bryan A. Whitson
    • , Nahush A. Mokadam
    • , Brandon J. Biesiadecki
    • , Federica Accornero
    • , John D. Hummel
    • , Peter J. Mohler
    • , Halina Dobrzynski
    • , Jichao Zhao
    •  & Vadim V. Fedorov
  • Article
    | Open Access

    Uveal melanoma is highly metastatic and unresponsive to checkpoint immunotherapy. Here, the authors present single-cell transcriptomics of 59,915 cells in 8 primary and 3 metastatic samples, highlighting the diversity of the tumour microenvironment.

    • Michael A. Durante
    • , Daniel A. Rodriguez
    • , Stefan Kurtenbach
    • , Jeffim N. Kuznetsov
    • , Margaret I. Sanchez
    • , Christina L. Decatur
    • , Helen Snyder
    • , Lynn G. Feun
    • , Alan S. Livingstone
    •  & J. William Harbour

News & Comment

  • Comment
    | Open Access

    Gardner and colleagues argue that efforts to conserve biodiversity should capitalise on current momentum in the realm of climate change policy.

    • Charlie J. Gardner
    • , Matthew J. Struebig
    •  & Zoe G. Davies
  • Comment
    | Open Access

    The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.

    • Christopher Bruhn
    •  & Marco Foiani
  • Comment
    | Open Access

    A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.

    • Mark Helm
    • , Frank Lyko
    •  & Yuri Motorin
  • Editorial
    | Open Access

    The amplified warming of the Arctic in recent decades has been related to extreme weather events over the mid-latitudes, but its relative importance compared to other influences is not yet well understood. A Nature Research collection highlights evidence from theoretical and observational studies, as well as implications for future extreme events.

  • Comment
    | Open Access

    The European Space Agency (ESA) recently selected Comet Interceptor as its first ‘fast’ (F-class) mission. It will be developed rapidly to share a launch with another mission and is unique, as it will wait in space for a yet-to-be-discovered comet.

    • Colin Snodgrass
    •  & Geraint H Jones
  • Comment
    | Open Access

    As climate change thaws the Arctic’s foundations, new subterranean waterways form and threaten to wash away and decompose carbon once locked in permafrost. In this Comment, Vonk and co-authors outline a cross-disciplinary strategy--with hydrology at the forefront--to better understand the fate of Arctic carbon.

    • J. E. Vonk
    • , S. E. Tank
    •  & M. A. Walvoord

Focus

From Brain to Behaviour

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From Brain to Behaviour

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

Fiona Carr, Jamie Horder, Sachin Ranade and Jerome Staal

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