Microscopic image of parasites in lung tissue

Impact of pulmonary African trypanosomes on the immunology and function of the lung

Sleeping sickness is a disease caused by Trypanosoma parasites. Mabille et al. study how the parasites (colourized in the image) affect respiratory function and lung immune responses.


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Latest Research articles

  • Quantum simulators allow for experimental studies of many-body systems in complex geometries, which has rarely been addressed by theory. Here the authors study many-body Hamiltonians on generic random graphs and show that many-body effects emerge only in a small class of exceptional, highly structured graphs.

    • Joseph Tindall
    • Amy Searle
    • Dieter Jaksch
    Article Open Access
  • Transformations of alcohols, which are ubiquitous in chemistry and are native functionalities in many natural products and bioactive molecules, are cornerstones of organic synthesis. Here the authors describe photocatalyzed cross-couplings of activated alcohols with α-amino acids, providing a direct approach for a variety of unnatural amino acids.

    • Yiman Gao
    • Jie Liu
    • Lingchao Cai
    Article Open Access
  • Tanner’s law describes the spreading dynamics of droplets made of Newtonian viscous fluids. Here, the authors demonstrate that this law remains valid for phase-separated binary liquids close to their critical point, and thus for all the associated universality class.

    • Raphael Saiseau
    • Christian Pedersen
    • Jean-Pierre Delville
    Article Open Access

Subjects within Physical sciences

  • Climate change and earlier snowmelt could potentially extend the growing season for alpine grassland plants. Here, the authors combine field and chamber controlled experiments to show that extending the summer period did not result in prolonged root and leaf growth.

    • Patrick Möhl
    • Raphael S. von Büren
    • Erika Hiltbrunner
    Article Open Access
  • Glacial erosion processes over geological timescales are poorly understood. Here the authors apply an observationally constrained model to reconstruct the evolving thermodynamics and transient erosional signature of the Eurasian Ice Sheet over the last 100,000-year ice age to reveal how it profoundly sculpted but also protected the landscape visible today

    • H. Patton
    • A. Hubbard
    • K. Andreassen
    Article Open Access

Subjects within Earth and environmental sciences

  • G protein coupled receptors (GPCRs) can couple to different Gα protein subfamilies either selectively or promiscuously. Here, the authors use computational approach to show that selectivity determinants are at the periphery of the GPCR—G protein interface and that promiscuous GPCRs more frequently sample the common rather than selective contacts.

    • Manbir Sandhu
    • Aaron Cho
    • Nagarajan Vaidehi
    Article Open Access
  • The linker for activation of T cells (LAT) protein is involved in the activation of T cells. Here the authors discover micron scale LAT condensation events downstream of singly bound T-cell receptors during T cell activation and characterise how LAT condensation timing affects downstream T cell signalling.

    • Darren B. McAffee
    • Mark K. O’Dair
    • Jay T. Groves
    Article Open Access
  • The presented Mean-Shift Super Resolution (MSSR) algorithm can extend spatial resolution within a single microscopy image. Its applicability extends across a wide range of experimental and instrumental configurations and it is compatible with other super-resolution microscopy approaches.

    • Esley Torres-García
    • Raúl Pinto-Cámara
    • Adán Guerrero
    Article Open Access

Subjects within Biological sciences

Subjects within Health sciences

  • Misinformation online can be shared by major political figures and organizations. Here, the authors developed a method to measure exposure to information from these sources on Twitter, and show how exposure relates to the quality of the content people share and their political ideology.

    • Mohsen Mosleh
    • David G. Rand
    Article Open Access
  • The COVID-19 pandemic has stimulated an important changes in online information access. Here, the authors analyse everyday web search interactions across 25,150 US ZIP codes revealing significant differences in how digital informational resources are mobilized by different communities.

    • Jina Suh
    • Eric Horvitz
    • Tim Althoff
    Article Open Access
  • Systemic risk and bank bailout approaches have been the source of discussions on scientific, financial and governmental forums. An artificial intelligence technique is proposed to inform equitable bailout decisions that minimise taxpayers’ losses.

    • Daniele Petrone
    • Neofytos Rodosthenous
    • Vito Latora
    Article Open Access
  • In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.

    • Anderson F. Brito
    • Elizaveta Semenova
    • Nuno R. Faria
    Article Open Access

Subjects within Scientific community and society

  • The rapid expansion and globalization of the seaweed production industry, combined with rising seawater temperatures and coastal eutrophication, has led to an increase in infectious diseases and pest outbreaks. Here, we propose a novel Progressive Management Pathway for improving Seaweed Biosecurity.

    • Elizabeth J. Cottier-Cook
    • Jennefe P. Cabarubias
    • Melba G. Bondad-Reantaso
    Comment Open Access
  • Association genetic studies and genome-scale CRISPR screens have recently identified ARF3 and TMEM251/LYSET/GCAF as Golgi-resident factors essential to brain and skeletal development. Here we discuss how even though the consequences of mutations in these genes affect endosomal and lysosomal compartments, the problem originates in the Golgi complex and may involve either the identity of the carrier vesicles or that of cargo molecules.

    • Vincent El Ghouzzi
    • Gaelle Boncompain
    Comment Open Access
  • Since 2020 Nature Communications has been considering Registered Reports for publication in the areas of cognitive neuroscience, human behaviour and psychology, and epidemiology. We are excited to announce the publication of our first Registered Report. With this milestone, we also want to open the format to all other areas of research.

    Editorial Open Access
  • We recently published our first Registered Report entitled ‘Value-free random exploration is linked to impulsivity’. We believe the format offers many benefits to strengthen hypothesis-driven research and are keen to share our experience with our readers as we open up the format to all fields of research. We interviewed the authors of the manuscript (Magda Dubois and Tobias Hauser) and one of the reviewers (Trevor Robbins) about their experience of the review process. We are editorially committed to take their comments on board to further improve our guidance and to optimally support our future authors.

    Q&A Open Access
  • Nature Communications is now welcoming Registered Report submissions from all fields of research (read our editorial here), and we want to encourage submissions from the ecology and evolutionary biology fields. To introduce this format to researchers in those fields, we interviewed two founding members of the Society for Open, Reliable, and Transparent Ecology and Evolutionary Biology (SORTEE), a network of researchers aimed at improving research practices in ecology, evolutionary biology, and related fields: Shinichi Nakagawa (Professor of Evolutionary Ecology and Synthesis at the University of New South Wales, UNSW) and Rose O’Dea (Secretary of SORTEE, postdoctoral researcher and fellow at the Wissenschaftskolleg zu Berlin). Below, they share their thoughts on how the fields of ecology and evolutionary biology can advance in reproducibility and transparency.

    Q&A Open Access
  • While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating diverse ancestries in these models to improve equity and accelerate biological discovery.

    • Sulagna Ghosh
    • Ralda Nehme
    • Lindy E. Barrett
    Comment Open Access

From brain to behaviour

On this page, we highlight some of the most exciting neuroscience papers that advance our understanding of the brain, covering neurodegeneration, neurological diseases, psychology, cognitive neuroscience, systems neuroscience, neurophysiology, neurotechnologies, computational neuroscience, and neurodevelopment.


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