The synthesis of ultrathin two-dimensional metastable metallic nanomaterials is highly challenging. Here, the authors report free-standing RhMo nanosheets with atomic thickness and a core/shell (metastable/stable phase) structure for high performance towards hydrogen oxidation.

Non-radiative recombination loss suppression is critical for boosting performance of organic solar cells. Here, the authors regulate self-organization of bulk-heterojunction in a non-monotonic manner, and achieve device efficiency over 19% with low non-radiative recombination loss down to 0.168 eV.

The construction of efficient photocatalyst system by utilizing hydrovoltaic technology bring promise but a challenge for photocatalytic water splitting. Here, the authors report a hydrovoltaic effect-enhanced photocatalytic system that shows high efficiency and quick kinetics of water splitting.

Diamination of allenes with two different acyclic and cyclic alkyl amines remains a daunting challenge. Here, the authors report a modular and practical diamination of allenes, which offers efficient syntheses of β,γ-diamino carboxylates and sulfones.

There has been a lot of interest in using antiferromagnets for magnetic memories, due to their fast dynamics, and resilience to stray fields. Such a memory was supposed to be switched by a spin-orbit torque. Here, Zhu and Ralph find that as a ferrimagnet approaches the magnetic compensation point, the spin-orbit torque acting on the ferrimagnet vanishes due to competing spin relaxation processes.

Elevation-dependent warming trends have been previously identified, but its effect on fire danger is still unclear. Here the authors show that there has been widespread increases in fire danger across the mountainous western US from 1979 to 2020 with most acute trends at high-elevation regions above 3000 m.

Observations are reported of HClO₃ and HClO₄ in the atmosphere and their widespread occurrence over the pan-Arctic during spring, providing further insights into atmospheric chlorine cycling in the polar environment.

Extreme ice sheet melt events in northeast Greenland occur after intense water vapor transport into northwest Greenland by atmospheric rivers. Through the foehn effect, the air becomes warmer and drier as it descends the ice sheet slope.

Thousands of industrial sites were found to be correlated with contaminated sites in the Arctic. Between 13,000 and 20,000 contaminated sites are likely to exist in the permafrost region, 26% of which will be affected by permafrost thaw before 2100.

The color of environmental noise, or degree of predictability in environmental variation, has important implications for ecosystem conservation and management. This study investigates the patterns and drivers of noise color across the US rivers.

G protein-coupled receptors are a major class of drug targets. Here, the authors develop a method whereby their biophysical and functional properties can be altered through directed evolution in mammalian cells, leading to variants exhibiting features such as high stability and expression, or increased allosteric coupling.

People with the rare Bombay-type O_h blood group can only be transfused with O_h blood. Here, the authors characterize a bacterial α−1,2-fucosidase that can convert universal O type into rare Bombay type blood.

The germinal centre (GC) response is characterized by regulated production of high affinity, class-switched antibodies in response to T-cell dependent antigens. Here authors show that the GC response is not only regulated at the transcriptional and protein levels, but also by the RNA-binding protein hnRNP F via alternative splicing of the co-stimulatory molecule CD40.

The generation of primitive macrophages remains a poorly understood process in humans. Here, the authors identify placental erythro-myeloid progenitors that give rise to foetal macrophages in the early human placenta and demonstrate that epigenetic silencing of the class II transactivator leads to downregulation of HLA-DR in these cells.

In this study, the authors use cryo-focused-ion-beammilling and cryo-electron tomography to image the apical complex of parasites in their native states. They report insights into the parasite invasion machinery in its protruded and retracted states in three dimensions, including all cytoskeletal assemblies, secretory organelles, and membranes intact.

Post-acute sequelae SARS-CoV-2 (PASC), also known as long COVID is a chronic and often debilitating condition that develops following acute disease. Here authors show that individuals who suffer from PASC symptoms at six month following infection are characterized by persisting immunological disfunction, affecting cellular and humoral components of mucosal immunity.

The timing of measles vaccination in infants affects the risk of infection in young children and the duration of protection provided. Here, the authors investigate optimal vaccination timing by characterising antibody kinetics following different vaccine schedules in two cohorts of children in southern China.

Duodenal cancer (DC) has complex subtypes and undergoes complicated morphological changes throughout progression, so understanding the molecular basis is crucial. Here, the authors perform a proteogenomics analysis of 156 DCs, revealing molecular subtypes as well as the roles of smoking, AARS1 and PARP1.

Despite medications, heart failure worsens with time with many patients dying within five years of diagnosis. Here the authors show that blocking purinergic receptors in the carotid body stops heart failure progression, improves its function, reduces sleep apneas and systemic inflammation in male rats.

Primary biliary cholangitis is a rare, chronic immune-mediated liver disease triggered by environmental exposures in genetically susceptible individuals. Here, the authors investigate the functional mechanism underlying the association of 19p13.3 variants with primary biliary cholangitis.

Old Masters used paints containing mixtures of oils and proteins, but we lack an understanding on how and why proteins were used. Here, the authors use egg yolk in combination with two pigments to evaluate how different repartition of proteinaceous binder can be used to control the flow behaviour as well as drying kinetics and chemistry of oil paints.

Here, using hypergraph modeling the authors show that surprising research (in terms of unexpected combinations of research contents and contexts) is associated with impact and arises from scientific outsiders solving problems in distant disciplines.

Availability of modern seed varieties in developing countries has had positive effects on households’ well-being. Here, the authors show that without support to maintain soil fertility, access to modern seed varieties increases primary forest clearance in DR Congo.

A more equitable global distribution of vaccines can benefit the world, while a multilateral benefit-sharing instrument needs to be developed to remove some of the disincentives for early equitable vaccines distribution globally.

Establishing sustainable approaches for human space exploration is key to achieve independency from terrestrial resources, as well as for ethical considerations. Here the authors highlight microbial biotechnologies that will support sustainable processes for space-based in situ resource utilization and loop-closure, and may be translatable to Earth applications.