The current throughput of conventional organic chemical synthesis is usually a few experiments for each operator per day. Here the authors develop a robotic system for ultra-high-throughput chemical synthesis, online characterization and large-scale condition screening of photocatalytic reactions.

All-solid-state batteries (ASSB) are designed to address the limitations of conventional lithium ion batteries. Here, authors developed a Nb1.60Ti0.32W0.08O5-δ negative electrode for ASSBs, which improves fast-charging capability and cycle stability.

Continuous and long-term monitoring of medicines in biological systems could offer personalized pharmacokinetic reports but is challenging due to the complexity of the biological environment in living organisms. Here, the authors present a photoelectrochemical biosensor with single atom Cu on TiO2-x as recognition unit for selective, precise, long-term tetracycline monitoring in living organisms.

The Greenberger-Horne-Zeilinger states are multipartite entangled quantum states with strong non-local entanglement. Here the authors generate large-scale states of this type with up to 60 qubits and show that discrete time crystals can effectively protect such fragile states.

Biological catch bonds counter-intuitively strengthen when pulled. Here, the authors present tuneable artificial catch bonds made from DNA for the study of biomimetic adhesion and the creation of force-strengthening materials.

Electric fields in the solar atmosphere are not studied as widely as the magnetic fields mainly due to small, short living signals. Here, the authors show measurement of an electric field associated with magnetic diffusion triggering an energetic event in the solar atmosphere.

Conservation agriculture is promoted as a sustainable solution in the changing climate, but its response to warming is unclear. Here, the authors report that conservation agriculture improves soil health and sustains crop yields under long-term warming compared to conventional agriculture.

This paper proposes an open-source, impact-based forecast for tropical cyclone population displacement using both cyclone forecasts and population settlements and vulnerabilities. This is applied to Tropical Cyclone Yasa, striking Fiji in 2020.

Effective surveillance of respiratory virus particles in air requires highly sensitive tools that can produce timely and accurate results. Here, the authors develop a device for detection of four respiratory viruses in air with high spatial viral resolution and test it in different settings.

Extremely light apatite δD values indicate deep-originated water in intracontinental granites and basalts from the North China Craton, probably from a stagnant slab within the mantle transition zone.

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via a modified molecular clutch model.

The circuitry underpinning visuomotor behaviors in flies is poorly understood. Here, the authors show that the underlying computations require bilateral electrical coupling to control turning dynamics and direction for effective course control.

Baobab is a long-lived tree that holds great economic, ecological, and cultural value. Here, the authors report haploid chromosome-level reference genome of Adansonia digitata and draft assemblies for a sibling tree, two trees from distinct locations in Africa, and a related species from Madagascar.

KLHDC2 is a promising E3 ligase for targeted protein degradation (TPD). In this study, the authors demonstrate that heterobifunctional degraders induce cooperative ternary complexes with KLHDC2 and BRD3. They highlight exit vector, neo-substrate, E3 ligase selectivity, and prodrug choice can effectively leverage C-degron E3s for TPD.

Monoclonal antibodies hold promise for combating serious respiratory virus infections but viruses may evolve to evade them. Here, using structural analysis, the authors show how human parainfluenza virus adapts to escape a powerful antibody by modulating its cell entry mechanism.

Evidence for comprehensive assessment of cardiovascular disease (CVD) burden attributable to high fasting plasma glucose (FPG) in China is limited. Here, the authors show CVD deaths attributable to high FPG varied substantially across China. Exposure to high FPG and population aging were the primary drivers of increased CVD burden.

Several approaches based on positron emission tomography (PET) are currently used to evaluate cancer response to immunotherapy. Here the authors report the results of a phase 1/2 trial evaluating a PET radiotracer, ⁶⁸Ga-grazytracer, for the imaging of granzyme B expression in patients treated with immune checkpoint inhibitors or CAR-T cell therapy.

Unfairness in AI healthcare models arise from biased correlations between sensitive attributes and disease data. Here, the authors show that the Attribute Neutral Framework reduces these biases and enhances fairness without compromising diagnostic accuracy.

Abnormal subchondral bone remodeling plays a pivotal role in the progression of osteoarthritis. Here, the authors reveal a negative feedback loop, RANKL-UCHL1-sCD13, which limits osteoclastogenesis in the subchondral bone to prevent osteoarthritis progression.

Effective surveillance of respiratory virus particles in air requires highly sensitive tools that can produce timely and accurate results. Here, the authors develop a device for detection of four respiratory viruses in air with high spatial viral resolution and test it in different settings.

Unfairness in AI healthcare models arise from biased correlations between sensitive attributes and disease data. Here, the authors show that the Attribute Neutral Framework reduces these biases and enhances fairness without compromising diagnostic accuracy.

This paper proposes an open-source, impact-based forecast for tropical cyclone population displacement using both cyclone forecasts and population settlements and vulnerabilities. This is applied to Tropical Cyclone Yasa, striking Fiji in 2020.

The study shows that India’s agricultural subsidies have driven significant groundwater depletion by incentivizing overproduction of water-intensive crops like rice and wheat. This impact is evident in both Punjab’s alluvial aquifers and Madhya Pradesh’s hard rock aquifers.

In this work, authors present an integral MCNP model of the ITER facility for radiation transport, addressing limitations of separate models for the Tokamak and Tokamak Complex. This model streamlines safety simulations, enhancing the robustness and simplicity of radiation safety analysis.

The study examines how land property rights impact land use efficiency (LUE) globally, based on the SDG 11.3.1 indicator. Secure rights improve LUE, with common law countries outperforming civil law countries, supporting sustainable land management.