Hyunwoo Yuk, Baoyang Lu et al.

3D printing of conducting polymers

Latest Research

Physical sciences

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  • Article
    | Open Access

    Neisseria meningitidis capsular polysaccharide (CPS) is a major virulence factor and vaccine formulations against Neisseria meningitidis serogroup A (NmA) contain O-acetylated CPS. Here, the authors provide mechanistic insights into CPS O-acetylation in NmA by determining the crystal structure of the O-acetyltransferase CsaC and NMR measurements further reveal that the CsaC-mediated reaction is regioselective for O3 and that the O4 modification results from spontaneous O-acetyl migration.

    • Timm Fiebig
    • , Johannes T. Cramer
    • , Andrea Bethe
    • , Petra Baruch
    • , Ute Curth
    • , Jana I. Führing
    • , Falk F. R. Buettner
    • , Ulrich Vogel
    • , Mario Schubert
    • , Roman Fedorov
    •  & Martina Mühlenhoff
  • Article
    | Open Access

    Designing efficient nanowire chip-based electrical and optical devices remains a challenge. Here, the authors present an axial p-n junction GaAs nanowire X-ray detector that enables achieving a spatial resolution of 200 nm; probing the internal electrical field and observing hot electron effects at the nanoscale.

    • Maximilian Zapf
    • , Maurizio Ritzer
    • , Lisa Liborius
    • , Andreas Johannes
    • , Martin Hafermann
    • , Sven Schönherr
    • , Jaime Segura-Ruiz
    • , Gema Martínez-Criado
    • , Werner Prost
    •  & Carsten Ronning
  • Article
    | Open Access

    Direct visualisation of site-specific strain variations of catalysts is needed to better understand catalytic properties. Here, the authors determine with attojoule precision that the well-known catalytic hysteresis phenomenon occurs at single particle level and involves three-dimensional strain field.

    • Aline R. Passos
    • , Amélie Rochet
    • , Luiza M. Manente
    • , Ana F. Suzana
    • , Ross Harder
    • , Wonsuk Cha
    •  & Florian Meneau

Earth and environmental sciences

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  • Article
    | Open Access

    Here, the authors perform a temporal multi-omic analysis of a minimalistic cellulose-degrading and methane-producing consortium at the strain level and estimate protein-to-RNA ratios and RNA-protein dynamics of the community simultaneously over time.

    • F. Delogu
    • , B. J. Kunath
    • , P. N. Evans
    • , M. Ø. Arntzen
    • , T. R. Hvidsten
    •  & P. B. Pope
  • Article
    | Open Access

    Soil age is thought to be an important driver of ecosystem development. Here, the authors perform a global survey of soil chronosequences and meta-analysis to show that, contrary to expectations, soil age is a relatively minor ecosystem driver at the biome scale once other drivers such as parent material, climate, and vegetation type are accounted for.

    • Manuel Delgado-Baquerizo
    • , Peter B. Reich
    • , Richard D. Bardgett
    • , David J. Eldridge
    • , Hans Lambers
    • , David A. Wardle
    • , Sasha C. Reed
    • , César Plaza
    • , G. Kenny Png
    • , Sigrid Neuhauser
    • , Asmeret Asefaw Berhe
    • , Stephen C. Hart
    • , Hang-Wei Hu
    • , Ji-Zheng He
    • , Felipe Bastida
    • , Sebastián Abades
    • , Fernando D. Alfaro
    • , Nick A. Cutler
    • , Antonio Gallardo
    • , Laura García-Velázquez
    • , Patrick E. Hayes
    • , Zeng-Yei Hseu
    • , Cecilia A. Pérez
    • , Fernanda Santos
    • , Christina Siebe
    • , Pankaj Trivedi
    • , Benjamin W. Sullivan
    • , Luis Weber-Grullon
    • , Mark A. Williams
    •  & Noah Fierer
  • Article
    | Open Access

    The early Eocene was characterized by exceptionally high global temperatures and no polar ice. Here, clumped isotope paleothermometry of glendonite calcite from the Danish Basin shows that these were formed in waters below 5 °C, indicating that regionalised cool episodes punctuated the background warmth of the early Eocene.

    • Madeleine L. Vickers
    • , Sabine K. Lengger
    • , Stefano M. Bernasconi
    • , Nicolas Thibault
    • , Bo Pagh Schultz
    • , Alvaro Fernandez
    • , Clemens V. Ullmann
    • , Paul McCormack
    • , Christian J. Bjerrum
    • , Jan Audun Rasmussen
    • , Iben Winther Hougård
    •  & Christoph Korte

Biological sciences

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  • Article
    | Open Access

    Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair, thereby ensuring the survival of the cells.

    • Elisabeth Anne Adanma Obara
    • , Diana Aguilar-Morante
    • , Rikke Darling Rasmussen
    • , Alex Frias
    • , Kristoffer Vitting-Serup
    • , Yi Chieh Lim
    • , Kirstine Juul Elbæk
    • , Henriette Pedersen
    • , Lina Vardouli
    • , Kamilla Ellermann Jensen
    • , Jane Skjoth-Rasmussen
    • , Jannick Brennum
    • , Lucie Tuckova
    • , Robert Strauss
    • , Christoffel Dinant
    • , Jiri Bartek
    •  & Petra Hamerlik
  • Article
    | Open Access

    Neisseria meningitidis capsular polysaccharide (CPS) is a major virulence factor and vaccine formulations against Neisseria meningitidis serogroup A (NmA) contain O-acetylated CPS. Here, the authors provide mechanistic insights into CPS O-acetylation in NmA by determining the crystal structure of the O-acetyltransferase CsaC and NMR measurements further reveal that the CsaC-mediated reaction is regioselective for O3 and that the O4 modification results from spontaneous O-acetyl migration.

    • Timm Fiebig
    • , Johannes T. Cramer
    • , Andrea Bethe
    • , Petra Baruch
    • , Ute Curth
    • , Jana I. Führing
    • , Falk F. R. Buettner
    • , Ulrich Vogel
    • , Mario Schubert
    • , Roman Fedorov
    •  & Martina Mühlenhoff
  • Article
    | Open Access

    Direct visualisation of site-specific strain variations of catalysts is needed to better understand catalytic properties. Here, the authors determine with attojoule precision that the well-known catalytic hysteresis phenomenon occurs at single particle level and involves three-dimensional strain field.

    • Aline R. Passos
    • , Amélie Rochet
    • , Luiza M. Manente
    • , Ana F. Suzana
    • , Ross Harder
    • , Wonsuk Cha
    •  & Florian Meneau

Health sciences

See All
  • Article
    | Open Access

    Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair, thereby ensuring the survival of the cells.

    • Elisabeth Anne Adanma Obara
    • , Diana Aguilar-Morante
    • , Rikke Darling Rasmussen
    • , Alex Frias
    • , Kristoffer Vitting-Serup
    • , Yi Chieh Lim
    • , Kirstine Juul Elbæk
    • , Henriette Pedersen
    • , Lina Vardouli
    • , Kamilla Ellermann Jensen
    • , Jane Skjoth-Rasmussen
    • , Jannick Brennum
    • , Lucie Tuckova
    • , Robert Strauss
    • , Christoffel Dinant
    • , Jiri Bartek
    •  & Petra Hamerlik
  • Article
    | Open Access

    DsbA-L upregulation prevents lipid-induced renal injury in diabetic nephropathy. Here, the authors show that DsbA-L knockout attenuates tubulointerstitial fibrosis in mice, and show that this occurs via activation of Smad3 and p53, which result in modulation of CTGF, a regulator of kidney fibrosis.

    • Xiaozhou Li
    • , Jian Pan
    • , Huiling Li
    • , Guangdi Li
    • , Xiangfeng Liu
    • , Bohao Liu
    • , Zhibiao He
    • , Zhengyu Peng
    • , Hongliang Zhang
    • , Yijian Li
    • , Xudong Xiang
    • , Xiangping Chai
    • , Yunchang Yuan
    • , Peilin Zheng
    • , Feng Liu
    •  & Dongshan Zhang

News & Comment

  • Editorial
    | Open Access

    Coastal regions are disproportionately affected by the impacts of climate change. Preserving the ecological, economic and societal benefits of these environments will rely on synergy across disciplines.

  • Editorial
    | Open Access

    The robustness of science is best revealed when independent investigations of the same problem arrive at similar conclusions. At Nature Communications, we commit to disregard from our editorial evaluation any competing works that are published while a submission to our journal is under review or under revision by the authors.

  • Comment
    | Open Access

    Bayesian brain theories suggest that perception, action and cognition arise as animals minimise the mismatch between their expectations and reality. This principle could unify cognitive science with the broader natural sciences, but leave key elements of cognition and behaviour unexplained.

    • Daniel Yon
    • , Cecilia Heyes
    •  & Clare Press
  • Comment
    | Open Access

    Single cell transcriptomics technologies have vast potential in advancing our understanding of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade of technological advancements in single-cell transcriptomics and highlight some of the recent discoveries enabled by this technology.

    • Sarah Aldridge
    •  & Sarah A. Teichmann
  • Comment
    | Open Access

    Controlling the hybridization of single atoms in suitable host materials opens unique opportunities for catalyst design, but equally faces many challenges. Here, we highlight emerging directions from the last, highly productive, decade in single-atom catalysis and identify frontiers for future research.

    • Sharon Mitchell
    •  & Javier Pérez-Ramírez

Focus

Inorganic, Nanoscale and Physical Chemistry

M. Eugenio Vázquez-Sentís/doi:10.1038/s41467-018-05183-8

Inorganic, Nanoscale and Physical Chemistry

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

Jacilynn Brant, Long Chen, Margherita Citroni and Ariane Vartanian

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