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Extracellular vesicles

Taking metabolism on the road

Extracellular vesicles (EVs) are a class of secreted membrane particles capable of transferring biological molecules between cells. Metabolomics measurements indicate that isolated EVs also have autonomous metabolic enzyme activities, including the unexpected identification of endogenous human asparaginase activity.

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Figure 1: Mechanisms by which extracellular vesicles (EVs) can alter organismal metabolism.

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Correspondence to Lucas B Sullivan.

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Sullivan, L. Taking metabolism on the road. Nat Chem Biol 13, 924–925 (2017). https://doi.org/10.1038/nchembio.2455

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  • DOI: https://doi.org/10.1038/nchembio.2455

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