Perspectives in 2019

Filter By:

Article Type
Year
  • This Perspective focuses on the chemical basis of ferroptotic cell death, discussing the prominent role of spontaneous chemical reactions, how they depend on enzyme-catalyzed processes and how to exploit this interplay for therapeutic benefit.

    • Marcus Conrad
    • Derek A. Pratt
    Perspective
  • This Perspective summarizes recent discoveries that have laid the foundation for targeted degradation therapeutics and discusses the current state of understanding and consideration involved in developing these protein degraders.

    • Philip P. Chamberlain
    • Lawrence G. Hamann
    Perspective