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New insights into the regulatory mechanisms of protein folding and turnover are informing the development of chemical tools and small molecules to treat proteostasis disorders.
Big Data analytic tools will be invaluable for extracting meaning from microbiome data to enable new solutions to global health problems and provide new insights into microbiology.
Young scientists should use conference time to maximize exposure of and get feedback on their work and to establish contacts within their scientific community.
Applying a rigorous chemical biology approach to the selection and validation of clinical targets will increase the success of drug discovery initiatives.
Public-private partnerships can reinvigorate precompetitive scientific research and de-risk drug discovery programs to help them meet demand for better and safer therapies.
The ENCODE project provides fundamental insights into the genome and large-scale science, inspiring future collaboration at the genomics–chemical biology interface.
Renewed interest in the biological significance and applied outcomes of metabolism is moving the field from static biochemical charts to multidimensional networks.