Editorials

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  • New insights into the regulatory mechanisms of protein folding and turnover are informing the development of chemical tools and small molecules to treat proteostasis disorders.

    Editorial
  • New computational and biochemical tools and informatic rules should spur research on a relatively underexplored class of molecules.

    Editorial
  • Big Data analytic tools will be invaluable for extracting meaning from microbiome data to enable new solutions to global health problems and provide new insights into microbiology.

    Editorial
  • Chemical biologists are advancing our understanding of light's role in the natural world and expanding its applications in the research lab.

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  • Young scientists should use conference time to maximize exposure of and get feedback on their work and to establish contacts within their scientific community.

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  • A collection of articles illustrates ways that synthetic biology tools and tactics both draw from and stimulate chemical biology research.

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  • Opportunities abound for chemical biologists to contribute to global initiatives designed to unlock the secrets of the human brain.

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  • Harnessing the immune system to treat disease will be facilitated by a greater understanding of the origins and roles of peptides in immunity.

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  • Ensuring that your research accomplishments and interests are accessible online broadens the reach of your scientific work.

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  • Increasing the reproducibility of translational and basic science research is a responsibility shared by the entire scientific community.

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  • Applying a rigorous chemical biology approach to the selection and validation of clinical targets will increase the success of drug discovery initiatives.

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  • Publication of a paper initiates the process of scientific exchange that requires the ongoing participation of authors.

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  • Public-private partnerships can reinvigorate precompetitive scientific research and de-risk drug discovery programs to help them meet demand for better and safer therapies.

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  • The Methods section of original research papers will be published online only starting in 2013.

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  • The launch of the International Chemical Biology Society represents an important step for chemical biology.

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  • The ENCODE project provides fundamental insights into the genome and large-scale science, inspiring future collaboration at the genomics–chemical biology interface.

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  • We are changing the way we evaluate papers to ensure timely dissemination of chemical biology research.

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  • Renewed interest in the biological significance and applied outcomes of metabolism is moving the field from static biochemical charts to multidimensional networks.

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  • Social media offer rapid and informal mechanisms to exchange ideas and build ties within the community.

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  • Funding organizations need to support young investigators to ensure the future of interdisciplinary research.

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