Aims & Scope

Nature Chemical Biology is an international monthly journal that provides a high-visibility forum for the publication of top-tier original research and commentary for the chemical biology community. Chemical biology combines the scientific ideas and approaches of chemistry, biology and allied disciplines to understand and manipulate biological systems with molecular precision. The journal publishes papers from the expanding community of chemical biologists, including contributions from chemists who are applying the principles and tools of chemistry to biological questions and from biologists who are interested in understanding and controlling biological processes at the molecular level.

We give priority to studies that report significant conceptual or practical advances in any area where chemistry and biology intersect. The journal is primarily interested in basic research, especially those studies that report new chemical or biological tools or present significant new molecular-level insights into the mechanisms underpinning biological processes. Additionally, because chemical biology approaches have broad utility for manipulating or engineering biological systems, the journal also considers manuscripts describing applied molecular studies at the chemistry-biology interface. Independent of the scientific area, we seek manuscripts that blend chemistry and biology in new ways, particularly those that provide major conceptual or methodological advances that are likely to open up innovative avenues of research in the field. The journal strives for a fair but comprehensive review process that emphasizes rigorous chemical and biological characterization.

In addition to publishing original research, Nature Chemical Biology is a forum for the exchange of ideas between scientists in the chemical and life sciences and a community resource for this emerging field. To this end, we publish content including scholarly reviews and perspectives, highlights of research published in our pages and in other journals, correspondence and commentaries that present topics of scientific and community interest.