Volume 7 Issue 4, April 2015

Volume 7 Issue 4

DNA nanotubes are attractive scaffolds for the assembly of complex arrays, and there is great interest in controlling their polydispersity and the sequence of rungs along their backbone. Now, Hanadi Sleiman, Gonzalo Cosa and co-workers have devised a solid-state synthesis to produce surface-grafted robust DNA nanotubes. Different rungs can be incorporated in a stepwise manner and each one is individually addressable. As shown on the cover, each rung is tagged with a fluorescent dye to enable visualization of nanotube growth at the single-molecule level.Article p295IMAGE: MELANIE BURGERCOVER DESIGN: KAREN MOORE

Thesis

  • Thesis |

    It's time to wake up and smell the chemistry, argues Michelle Francl.

    • Michelle Francl

Books and Arts

Research Highlights

Blogroll

News and Views

  • News & Views |

    The spontaneous syntheses of some of life's building blocks from simple precursors have previously been demonstrated in isolation. Now it has been shown that they might all emerge from just one set of ingredients.

    • Paul J. Bracher
  • News & Views |

    Building on our understanding of the chemical bond, advances in synthetic chemistry, and large-scale computation, materials design has now become a reality. From a pool of 400 unknown compositions, 15 new compounds have been realized that adopt the predicted structures and properties.

    • Aron Walsh
  • News & Views |

    A supramolecular polymer comprising stacked artificial chromophores to which zinc(II) complexes are appended is able to respond to enzymatic hydrolysis in aqueous solution. The assembly of molecules can twist reversibly and quickly in response to changes in the type of adenosine phosphate present.

    • David B. Amabilino
  • News & Views |

    Supramolecular assembly has been used to design and create new proteins capable of performing biomimetic functions in complex environments such as membranes and inside living cells.

    • Arnold J. Boersma
    •  & Gerard Roelfes
  • News & Views |

    Identifying the contribution of different surface sites to the overall kinetics of molecular desorption from solid surfaces is difficult even when using single crystals. A new technique that combines molecular beams with UV−UV double resonance spectroscopy resolves this problem for the case of carbon monoxide on Pt(111).

    • Francisco Zaera

Review

  • Review Article |

    Ferroelectric materials hold much promise for the development of devices such as nonvolatile memories, sensors and nonlinear optic materials. This Review describes the molecular features required to devise organic molecular ferroelectrics, and presents the supramolecular chemistry strategies available for controlling molecular organization and dynamics across different length scales.

    • Alok S. Tayi
    • , Adrien Kaeser
    • , Michio Matsumoto
    • , Takuzo Aida
    •  & Samuel I. Stupp

Articles

  • Article |

    DNA nanotubes are attractive building blocks for the assembly of complex arrays. An efficient solid-state synthesis for producing surface-grafted, robust nanotubes has now been devised. Rungs are incorporated in a stepwise manner so that each one is addressable. Using fluorescent tags, the nanotube growth was visualized at the single-molecule level.

    • Amani A. Hariri
    • , Graham D. Hamblin
    • , Yasser Gidi
    • , Hanadi F. Sleiman
    •  & Gonzalo Cosa
  • Article |

    A minimal cell — one that has all the minimum requirements for life — is still a complex entity comprising informational, compartment-forming and metabolic subsystems. Here it is shown that, contrary to previous assumptions, a common prebiotically plausible chemistry can give rise to building blocks for all the subsystems.

    • Bhavesh H. Patel
    • , Claudia Percivalle
    • , Dougal J. Ritson
    • , Colm D. Duffy
    •  & John D. Sutherland
  • Article |

    A method to predict the stability, structure and properties of as-yet-unreported materials has been devised. For 18-valence electron ABX materials, 15 such ‘missing’ compounds identified to be thermodynamically stable were successfully synthesized, and showed crystal structures and properties in good agreement with the predicted ones.

    • Romain Gautier
    • , Xiuwen Zhang
    • , Linhua Hu
    • , Liping Yu
    • , Yuyuan Lin
    • , Tor O. L. Sunde
    • , Danbee Chon
    • , Kenneth R. Poeppelmeier
    •  & Alex Zunger
  • Article |

    Biopolymers adopt functional tertiary structures through folding and multiplex formation. Synthetic molecules with protein-like dimensions — monodisperse cyclic porphyrin polymers with diameters of 13–21 nm — have now been shown to exhibit biomimetic self-organization by forming nested structures on a gold surface. These assemblies are formed both under vacuum and during deposition from solution.

    • Dmitry V. Kondratuk
    • , Luís M. A. Perdigão
    • , Ayad M. S. Esmail
    • , James N. O'Shea
    • , Peter H. Beton
    •  & Harry L. Anderson
  • Article |

    Externally applied mechanical forces can steer molecules along reaction paths that are otherwise inaccessible. Single-molecule force spectroscopy has now been used to quantify the force required to induce symmetry-forbidden reactivity in three different reactions and compare their behaviour to that of the symmetry-allowed analogues.

    • Junpeng Wang
    • , Tatiana B. Kouznetsova
    • , Zhenbin Niu
    • , Mitchell T. Ong
    • , Hope M. Klukovich
    • , Arnold L. Rheingold
    • , Todd J. Martinez
    •  & Stephen L. Craig
  • Article |

    Photoelectrochemical water-splitting produces hydrogen at the cathode and oxygen at the anode. The anode reaction is, however, kinetically unfavourable. Now, reduction of water at the cathode has been combined with oxidation of 5-hydroxymethylfurfural at the anode resulting in a photoelectrochemical cell that produces fuel and a useful platform chemical.

    • Hyun Gil Cha
    •  & Kyoung-Shin Choi
  • Article |

    Designing synthetic molecular receptors that can differentiate between specific monosaccharide guests is very challenging. Now, a helically folded oligoamide that selectively encapsulates fructose has been designed using an iterative approach that exploits the modular structure of folded synthetic oligomer sequences, in conjunction with molecular modelling and structural characterization.

    • Nagula Chandramouli
    • , Yann Ferrand
    • , Guillaume Lautrette
    • , Brice Kauffmann
    • , Cameron David Mackereth
    • , Michel Laguerre
    • , Didier Dubreuil
    •  & Ivan Huc
  • Article |

    Two metallacages containing Pt(II) phosphine centres bridged by organic donors are shown to display dynamic emission behaviour across a range of concentrations. At low concentrations, the individual cages emit. At high concentrations, or on introduction of additional solvents, aggregation occurs that manifests in colour-tunable fluorescence and white-light emission in THF.

    • Xuzhou Yan
    • , Timothy R. Cook
    • , Pi Wang
    • , Feihe Huang
    •  & Peter J. Stang
  • Article |

    Long-lived molecular collision complexes — or ‘resonances’ — are difficult to identify experimentally. Now crossed-beam experiments and quantum calculations are reported for rotationally inelastic CO−He collisions at energies corresponding to temperatures as low as 4 K. Quantum dynamical resonances that are predicted by theory were detected and fully characterized.

    • Astrid Bergeat
    • , Jolijn Onvlee
    • , Christian Naulin
    • , Ad van der Avoird
    •  & Michel Costes
  • Article |

    Interlocked molecules represent some of the most challenging synthetic targets in terms of non-natural products. It has now been demonstrated how a cyclic [3]catenane composed of three mutually interpenetrating rings can be prepared in two stages using a selective imine exchange reaction on a self-assembled triangular precursor.

    • Christopher S. Wood
    • , Tanya K. Ronson
    • , Ana M. Belenguer
    • , Julian J. Holstein
    •  & Jonathan R. Nitschke

In Your Element

  • In Your Element |

    Eric Ansoborlo and Richard Wayne Leggett discuss the chemical and radiological characteristics that make caesium a captivating element but also a troublesome contaminant.

    • Eric Ansoborlo
    •  & Richard Wayne Leggett

Erratum