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Taking chemical technology from the bench to the consumer is a formidable challenge, but it is how research can ultimately benefit wider society. Companies are now beginning to incorporate metal–organic frameworks into commercial products, heralding a new era for the field.
Nitric oxide (NO) is an important signalling molecule in biological systems, but it is unclear exactly how it interacts with some metalloproteins. Now, a collection of articles in this issue reveal how NO binds to proteins containing type-1 copper sites.
Chemistry research and education face challenges anywhere in the world, but more so in less developed — or less stable — economies. These countries and their more economically fortunate neighbours can all contribute to the development of chemistry and its ability to tackle local and global issues.
The modification of proteins with fluorophores, drugs and polymers is required for many applications, yet conjugation reactions often generate a heterogeneous mixture of products. A collection of articles in this issue focuses on methods to modify proteins in a site-selective manner.