Volume 6 Issue 11, November 2004

Volume 6 Issue 11

A three-dimensional model showing intercisternal connections (red and yellow) forming during intra-Golgi transport.


News and Views

  • News & Views |

    Over more than three decades, sporadic and circumstantial evidence has accumulated to suggest that nuclear actin has crucial functions in RNA polymerase II-based transcription. Now, using a biochemical approach, β-actin has been identified as a highly specific, constitutive component of the active transcriptional complex required for formation of the pre-initiation transcription complex.

    • Werner W. Franke
  • News & Views |

    The MRL protein family is emerging as a new connection between signalling, adhesion and cell motility. Two members, lamellipodin and RIAM, can regulate both actin assembly and cell adhesion, which raises many questions about how their interactions with Ena/VASP proteins, Ras-related GTPases and membranes orchestrate these key processes.

    • John A. Legg
    •  & Laura M. Machesky

Book Review



Cell of the Month



Brief Communication


  • Focus |

    Focus on cell biology of disease

    This section contains all material on the topic of the cell biology of disease published in Nature Cell Biology to date including original research papers, Reviews, Perspectives, Commentaries and News and Views. View the current focus issue from November 2004.