In the chicken embryo, monocytes foster a pro-angiogenic microenvironment in advance of angiogenesis by depositing migrasomes enriched in angiogenic factors.

See Zhang et al.

Tanaka et al. generate salivary gland organoids from human induced pluripotent stem cells that serve as a model for salivary gland development and SARS-CoV-2 infection.

See Tanaka et al.

Beucher et al. show that the lncRNA promoter HASTER, which is antisense to HNF1A, is a cell-specific cis-regulatory element that stabilizes HNF1A through positive and negative feedback loops, and that HASTER deletion can cause diabetes.

See Beucher et al.

Bao et al. show that differential adhesion force, mediated by a stem-cell-specific cadherin code, integrates with cell cortical tension to drive morphogenesis in synthetic embryos.

See Bao et al.

An apical spectrin network in endothelial cells transmits mechanical forces in response to shear flow-induced stress in a mechanism mediated by hyaluronic acid and PIEZO1.

See Mylvaganam et al.

Skin homeostasis and regeneration

See Sedov et al.

Fat-to-neuron lipid signalling

See Savini et al.and News & Views by Brunet

Phosphoinositide metabolism

See Walpole et al.and News & Views by Baskin

The expanding universe of small RNAs

See Shi et al.

Immune tolerance in stem cells

See Pinho et al. and News & Views by Lengerke

A monoastral spindle controls cell fate

See Pomp et al.

Imaging nuclear transport

See Chowdhury et al.